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公开(公告)号:US20120270922A1
公开(公告)日:2012-10-25
申请号:US13392196
申请日:2010-08-26
IPC分类号: A61K31/7052 , A61P27/02 , A61P29/00 , A61P35/00 , A61P9/00
CPC分类号: A61K31/7105 , A61K38/177 , C12N15/1138 , C12N2310/141 , C12N2330/10 , C12N2330/51
摘要: This invention provides an antiangiogenic agent having a higher treatment effect than those of conventional antiangiogenic agents, and a method for inhibiting angiogenesis using the same. An antiangiogenic agent comprising at least one miRNA type selected from the group consisting of miRNAs, pre-miRNAs, and pri-miRNAs, each having a miRNA activity on VE-cadherin.
摘要翻译: 本发明提供了具有比常规抗血管生成剂更高治疗效果的抗血管生成剂,以及使用其的抑制血管发生的方法。 一种抗血管生成剂,其包含选自miRNA,前miRNA和pri-miRNA中的至少一种miRNA型,其各自在VE-钙粘蛋白上具有miRNA活性。