公开(公告)号：US07351259B2

公开(公告)日：2008-04-01

申请号：US10843223

申请日：2004-05-10

申请人： Gary Swinford ,  Jay N. Wilkins ,  Cory Williamson ,  William E. Clem ,  Erik G. Green ,  Martin B. Albini

发明人： Gary Swinford ,  Jay N. Wilkins ,  Cory Williamson ,  William E. Clem ,  Erik G. Green ,  Martin B. Albini

IPC分类号： A61F2/24

CPC分类号： A61F2/2451 ,  Y10S623/904

摘要： A device for modifying the shape of a mitral valve annulus. In one embodiment, the device includes a connector disposed between first and second anchors, the first and second anchors each adapted to be deployed in a coronary sinus adjacent the mitral valve annulus to anchor the device in the coronary sinus; and an actuation element adapted to receive a proximally or distally directed actuation force from an actuator and to transmit the actuation force to the first and second anchors simultaneously. The invention also includes a system for modifying the shape of a mitral valve annulus, including a percutaneous deployment apparatus, including an actuator; and a percutaneous mitral valve annuloplasty device with a connector disposed between first and second anchors, the first and second anchors each adapted to be deployed in a coronary sinus adjacent the mitral valve annulus to anchor the device in the coronary sinus; and an actuation element adapted to receive a distally proximally directed actuation force from the actuator and to transmit the actuation force to the first and second anchors simultaneously. The invention also includes a method of using such devices and systems.

摘要翻译： 用于改变二尖瓣环的形状的装置。 在一个实施例中，该装置包括设置在第一和第二锚固件之间的连接器，第一和第二锚固件各自适于部署在邻近二尖瓣环的冠状窦中，以将装置锚定在冠状窦中; 以及致动元件，其适于从致动器接收近端或远端定向的致动力并且将致动力同时传递到第一和第二锚定器。 本发明还包括用于改变二尖瓣环的形状的系统，包括包括致动器的经皮展开装置; 以及具有设置在第一和第二锚固件之间的连接器的经皮二尖瓣瓣环成形术装置，所述第一和第二锚固件各自适于部署在邻近所述二尖瓣环的冠状窦中，以将所述装置锚定在冠状窦中; 以及致动元件，其适于从所述致动器接收远侧近端定向的致动力并将所述致动力同时传递到所述第一和第二锚固件。 本发明还包括使用这种装置和系统的方法。

公开(公告)号：US06596005B1

公开(公告)日：2003-07-22

申请号：US09670416

申请日：2000-09-26

申请人： Bill Kanz ,  Denise Drummond ,  Robert Barry ,  Paul A. Hirst ,  Mark Wyzgala ,  Gary Swinford ,  Edward Wulfman ,  Tom Clement ,  Tom Kadavy

发明人： Bill Kanz ,  Denise Drummond ,  Robert Barry ,  Paul A. Hirst ,  Mark Wyzgala ,  Gary Swinford ,  Edward Wulfman ,  Tom Clement ,  Tom Kadavy

IPC分类号： A61D102

CPC分类号： A61B17/320758 ,  A61B17/320725 ,  A61B2017/003 ,  A61B2017/00557 ,  A61B2017/00867 ,  A61B2017/320004 ,  A61B2017/320733 ,  A61B2017/320766

摘要： A catheter including an elongate drive shaft having a proximal end and a distal end, an ablation burr disposed at the distal end expandable between a first position and a second position, wherein in the second position has a greater transverse dimension than in the first position. The catheter of the present invention can include a mechanism for positioning the burr eccentrically within a vessel lumen. In this context, expansion means that the burr can ablate a lumen having a larger diameter than the diameter of the lumen of the guide catheter to which the device is advanced.

摘要翻译： 包括具有近端和远端的细长驱动轴的导管，设置在远端的消融毛刺可在第一位置和第二位置之间扩张，其中在第二位置具有比在第一位置更大的横向尺寸。 本发明的导管可以包括用于将毛刺偏心地定位在血管腔内的机构。 在这种情况下，膨胀意味着毛刺可以烧蚀具有比该装置前进的导管的内腔直径更大的直径的内腔。

公开(公告)号：US07300462B2

公开(公告)日：2007-11-27

申请号：US11276082

申请日：2006-02-13

申请人： Gary Swinford ,  Jay N. Wilkins ,  Cory Williamson ,  William E. Clem ,  Erik G. Green ,  Martin B. Albini

发明人： Gary Swinford ,  Jay N. Wilkins ,  Cory Williamson ,  William E. Clem ,  Erik G. Green ,  Martin B. Albini

IPC分类号： A61F2/24

CPC分类号： A61F2/2451 ,  Y10S623/904

摘要： A device for modifying the shape of a mitral valve annulus. In one embodiment, the device includes a connector disposed between first and second anchors, the first and second anchors each adapted to be deployed in a coronary sinus adjacent the mitral valve annulus to anchor the device in the coronary sinus; and an actuation element adapted to receive a proximally or distally directed actuation force from an actuator and to transmit the actuation force to the first and second anchors simultaneously. The invention also includes a system for modifying the shape of a mitral valve annulus, including a percutaneous deployment apparatus, including an actuator; and a percutaneous mitral valve annuloplasty device with a connector disposed between first and second anchors, the first and second anchors each adapted to be deployed in a coronary sinus adjacent the mitral valve annulus to anchor the device in the coronary sinus; and an actuation element adapted to receive a distally proximally directed actuation force from the actuator and to transmit the actuation force to the first and second anchors simultaneously. The invention also includes a method of using such devices and systems.

摘要翻译： 用于改变二尖瓣环的形状的装置。 在一个实施例中，该装置包括设置在第一和第二锚固件之间的连接器，第一和第二锚固件各自适于部署在邻近二尖瓣环的冠状窦中，以将装置锚定在冠状窦中; 以及致动元件，其适于从致动器接收近端或远端定向的致动力并且将致动力同时传递到第一和第二锚定器。 本发明还包括用于改变二尖瓣环的形状的系统，包括包括致动器的经皮展开装置; 以及具有设置在第一和第二锚固件之间的连接器的经皮二尖瓣瓣环成形术装置，所述第一和第二锚固件各自适于展开在邻近所述二尖瓣环的冠状窦中，以将所述装置锚定在冠状窦中; 以及致动元件，其适于从所述致动器接收远侧近端定向的致动力并将所述致动力同时传递到所述第一和第二锚固件。 本发明还包括使用这种装置和系统的方法。

公开(公告)号：US06569146B1

公开(公告)日：2003-05-27

申请号：US09642627

申请日：2000-08-18

申请人： Dennis Werner ,  David H. Dillard ,  Ray Fei ,  Gary Swinford ,  Verivada Chandru Chandrasekaran ,  Tim J. Johnson

发明人： Dennis Werner ,  David H. Dillard ,  Ray Fei ,  Gary Swinford ,  Verivada Chandru Chandrasekaran ,  Tim J. Johnson

IPC分类号： A61M3100

CPC分类号： A61B17/22 ,  A61B17/00491 ,  A61B2017/22038 ,  A61B2017/22054 ,  A61B2017/22067 ,  A61B2017/22082 ,  A61B2017/320004

摘要： A method for treating loosely formed, friable or fragile lesions in a patient's blood vessel. A catheter having a pair of sealing mechanisms is advanced such that the sealing mechanisms are positioned distal to and proximal to the lesion. The sealing mechanisms are activated to seal the vessel on either side of the lesion. A medication is then delivered through the catheter to the sealed area of the vessel. The medication interacts with the lesion in order to partially or completely solidify it. Once the lesion is solidified, the catheter is removed and the lesion can be treated with a conventional intravascular device.

摘要翻译： 一种用于治疗患者血管中松散形成的，易碎的或易碎的病变的方法。 具有一对密封机构的导管被推进，使得密封机构位于病变的远侧和近侧。 激活密封机构以密封病变两侧的血管。 然后将药物通过导管输送到容器的密封区域。 药物与病变相互作用以部分或完全固化。 一旦病变固化，导管被移除，病变可用常规的血管内装置治疗。

公开(公告)号：US6146395A

公开(公告)日：2000-11-14

申请号：US262502

申请日：1999-03-04

申请人： Bill Kanz ,  Denise Drummond ,  Robert Barry ,  Paul A. Hirst ,  Mark Wyzgala ,  Gary Swinford ,  Edward Wulfman ,  Tom Clement ,  Tom Kadavy

发明人： Bill Kanz ,  Denise Drummond ,  Robert Barry ,  Paul A. Hirst ,  Mark Wyzgala ,  Gary Swinford ,  Edward Wulfman ,  Tom Clement ,  Tom Kadavy

IPC分类号： A61B17/00 ,  A61B17/22 ,  A61B17/32 ,  A61B1/02

CPC分类号： A61B17/320758 ,  A61B17/320725 ,  A61B2017/003 ,  A61B2017/00557 ,  A61B2017/00867 ,  A61B2017/320004 ,  A61B2017/320733 ,  A61B2017/320766

摘要： A catheter including an elongate drive shaft having a proximal end and a distal end, an ablation burr disposed at the distal end which can be drawn proximally to engage with a burr deflector surface of the drive shaft in order to be displaced transversely to remove plaque.

摘要翻译： 包括具有近端和远端的细长驱动轴的导管，设置在远端处的消融毛刺，其可以向近侧拉伸以与驱动轴的毛刺偏转器表面接合，以横向移位以去除斑块。

公开(公告)号：US20060116758A1

公开(公告)日：2006-06-01

申请号：US11276082

申请日：2006-02-13

申请人： Gary Swinford ,  Jay Wilkins ,  Cory Williamson ,  William Clem ,  Erik Green ,  Martin Albini

发明人： Gary Swinford ,  Jay Wilkins ,  Cory Williamson ,  William Clem ,  Erik Green ,  Martin Albini

IPC分类号： A61F2/24

CPC分类号： A61F2/2451 ,  Y10S623/904

摘要： A device for modifying the shape of a mitral valve annulus. In one embodiment, the device includes a connector disposed between first and second anchors, the first and second anchors each adapted to be deployed in a coronary sinus adjacent the mitral valve annulus to anchor the device in the coronary sinus; and an actuation element adapted to receive a proximally or distally directed actuation force from an actuator and to transmit the actuation force to the first and second anchors simultaneously. The invention also includes a system for modifying the shape of a mitral valve annulus, including a percutaneous deployment apparatus, including an actuator; and a percutaneous mitral valve annuloplasty device with a connector disposed between first and second anchors, the first and second anchors each adapted to be deployed in a coronary sinus adjacent the mitral valve annulus to anchor the device in the coronary sinus; and an actuation element adapted to receive a distally proximally directed actuation force from the actuator and to transmit the actuation force to the first and second anchors simultaneously. The invention also includes a method of using such devices and systems.

摘要翻译： 用于改变二尖瓣环的形状的装置。 在一个实施例中，该装置包括设置在第一和第二锚固件之间的连接器，第一和第二锚固件各自适于部署在邻近二尖瓣环的冠状窦中，以将装置锚定在冠状窦中; 以及致动元件，其适于从致动器接收近端或远端定向的致动力并且将致动力同时传递到第一和第二锚定器。 本发明还包括用于改变二尖瓣环的形状的系统，包括包括致动器的经皮展开装置; 以及具有设置在第一和第二锚固件之间的连接器的经皮二尖瓣瓣环成形术装置，所述第一和第二锚固件各自适于部署在邻近所述二尖瓣环的冠状窦中，以将所述装置锚定在冠状窦中; 以及致动元件，其适于从所述致动器接收远侧近端定向的致动力并将所述致动力同时传递到所述第一和第二锚固件。 本发明还包括使用这种装置和系统的方法。

公开(公告)号：US20050149084A1

公开(公告)日：2005-07-07

申请号：US11070446

申请日：2005-03-01

申请人： Bill Kanz ,  Denise Drummond ,  Robert Barry ,  Paul Hirst ,  Mark Wyzgala ,  Gary Swinford ,  Edward Wulfman ,  Tom Clement ,  Tom Kadavy

发明人： Bill Kanz ,  Denise Drummond ,  Robert Barry ,  Paul Hirst ,  Mark Wyzgala ,  Gary Swinford ,  Edward Wulfman ,  Tom Clement ,  Tom Kadavy

IPC分类号： A61B17/00 ,  A61B17/22 ,  A61B17/32

CPC分类号： A61B17/320758 ,  A61B17/320725 ,  A61B2017/003 ,  A61B2017/00557 ,  A61B2017/00867 ,  A61B2017/320004 ,  A61B2017/320733 ,  A61B2017/320766

摘要： A catheter including an elongate drive shaft having a proximal end and a distal end, an ablation burr disposed at the distal end expandable between a first position and a second position, wherein in the second position has a greater transverse dimension than in the first position. The catheter of the present invention can include a mechanism for positioning the burr eccentrically within a vessel lumen. In this context, expansion means that the burr can ablate a lumen having a larger diameter than the diameter of the lumen of the guide catheter to which the device is advanced.

摘要翻译： 包括具有近端和远端的细长驱动轴的导管，设置在远端的消融毛刺可在第一位置和第二位置之间扩张，其中在第二位置具有比在第一位置更大的横向尺寸。 本发明的导管可以包括用于将毛刺偏心地定位在血管腔内的机构。 在这种情况下，膨胀意味着毛刺可以烧蚀具有比该装置前进的导管的内腔直径更大的直径的内腔。

公开(公告)号：US20050004667A1

公开(公告)日：2005-01-06

申请号：US10843223

申请日：2004-05-10

申请人： Gary Swinford ,  Jay Wilkins ,  Cory Williamson ,  William Clem ,  Erik Green ,  Martin Albini

发明人： Gary Swinford ,  Jay Wilkins ,  Cory Williamson ,  William Clem ,  Erik Green ,  Martin Albini

IPC分类号： A61F2/24

CPC分类号： A61F2/2451 ,  Y10S623/904

摘要： A device for modifying the shape of a mitral valve annulus. In one embodiment, the device includes a connector disposed between first and second anchors, the first and second anchors each adapted to be deployed in a coronary sinus adjacent the mitral valve annulus to anchor the device in the coronary sinus; and an actuation element adapted to receive a proximally or distally directed actuation force from an actuator and to transmit the actuation force to the first and second anchors simultaneously. The invention also includes a system for modifying the shape of a mitral valve annulus, including a percutaneous deployment apparatus, including an actuator; and a percutaneous mitral valve annuloplasty device with a connector disposed between first and second anchors, the first and second anchors each adapted to be deployed in a coronary sinus adjacent the mitral valve annulus to anchor the device in the coronary sinus; and an actuation element adapted to receive a distally proximally directed actuation force from the actuator and to transmit the actuation force to the first and second anchors simultaneously. The invention also includes a method of using such devices and systems.

摘要翻译： 用于改变二尖瓣环的形状的装置。 在一个实施例中，该装置包括设置在第一和第二锚固件之间的连接器，第一和第二锚固件各自适于部署在邻近二尖瓣环的冠状窦中，以将装置锚定在冠状窦中; 以及致动元件，其适于从致动器接收近端或远端定向的致动力并且将致动力同时传递到第一和第二锚定器。 本发明还包括用于改变二尖瓣环的形状的系统，包括包括致动器的经皮展开装置; 以及具有设置在第一和第二锚固件之间的连接器的经皮二尖瓣瓣环成形术装置，所述第一和第二锚固件各自适于展开在邻近所述二尖瓣环的冠状窦中，以将所述装置锚定在冠状窦中; 以及致动元件，其适于从所述致动器接收远侧近端定向的致动力并将所述致动力同时传递到所述第一和第二锚固件。 本发明还包括使用这种装置和系统的方法。