公开(公告)号：US06638993B2

公开(公告)日：2003-10-28

申请号：US10015878

申请日：2001-12-12

申请人： Bhawan Patel ,  David L. Morris ,  Geoffrey Haas ,  William O. Burke, III

发明人： Bhawan Patel ,  David L. Morris ,  Geoffrey Haas ,  William O. Burke, III

IPC分类号： C08K509

CPC分类号： C08K3/34 ,  C08K3/015 ,  C08K5/0058 ,  C08L21/00 ,  C08L23/16

摘要： Certain non-silicone vulcanized rubber articles made from at least a majority by weight of ethylene-propylene-diene modified (terpolymer) rubber (such as, without limitation, EPDM and/or NBR) that include silver-based compounds to provide highly desirable long-term antimicrobial characteristics within the cured rubber articles, at least a portion of which exhibits a color other than black, are provided. Such articles are in either solid or blown (foam or sponge) state (or combinations of both in multilayered forms, either all colored or individual layers colored) that can be utilized in a variety of different applications. As silver-based compounds are deleteriously affected by utilization of standard curing agents and curing accelerators, such as sulfur-based compounds and/or systems, the ability to provide such an effective antimicrobial vulcanized rubber article is rather difficult. However, this invention encompasses the presence of different non-sulfur-based curing systems and agents, such as peroxides, as one example, that permit vulcanization and do not irreversibly bind silver ions thereto, thereby resulting in long-term antimicrobial performance of the ultimate rubber article itself. The rubber articles must also comprise fillers and may also include plasticizers to provide desired characteristics of dimensional stability, stiffness, flexural modulus, tensile strength, abrasion resistance, elongation, and the like, for the ultimate rubber article, while simultaneously and surprisingly both enhancing the control of antimicrobial efficacy of the rubber article and not deleteriously binding to the available silver to permit coloring of the target rubber as well.

公开(公告)号：US06641842B2

公开(公告)日：2003-11-04

申请号：US10015872

申请日：2001-12-12

申请人： Erik Laridon ,  Geoffrey Haas ,  Robert Dankel

发明人： Erik Laridon ,  Geoffrey Haas ,  Robert Dankel

IPC分类号： A61K914

CPC分类号： A61K33/38 ,  A61K33/42

摘要： Improvements in increasing the amount of surface-available silver in thermoplastic articles comprising certain silver-containing antimicrobial agents. Such an invention requires the incorporation of a sufficient amount of a carboxylic acid salt within the thermoplastic article simultaneously with the necessary silver-containing antimicrobial agent. Certain carboxylic acid salts are standard acid scavengers and lubricants for certain thermoplastic applications; however, the amounts required within this inventive thermoplastic article are in excess of that commonly added within such articles, and the types of acid scavengers possibly added within such target thermoplastic articles are preferably neutralized hydrotalcite compounds, thereby permitting the carboxylic acid salt to function in the inventive manner. Surprisingly, such a high amount of such standard salts, as well as potentially other non-standard salts, present within the target thermoplastic cause the release of greater amounts of silver to the target article's surface, thereby permitting a greater degree of antimicrobial activity, among other potential benefits for such an increase in surface-available silver. Methods of producing such inventive thermoplastics are also encompassed within this invention.