公开(公告)号：US08787651B2

公开(公告)日：2014-07-22

申请号：US13247991

申请日：2011-09-28

申请人： Steven Potts ,  Trevor Johnson ,  Frank Voelker ,  George David Young

发明人： Steven Potts ,  Trevor Johnson ,  Frank Voelker ,  George David Young

IPC分类号： G06K9/00

CPC分类号： G06T7/0014 ,  G06T7/38 ,  G06T2207/10056 ,  G06T2207/20104 ,  G06T2207/30096

摘要： Feature analysis on consecutive tissue sections (FACTS) includes obtaining a plurality of consecutive tissue sections from a tissue sample, staining the sections with at least one biomarker, obtaining a digital image thereof, and identifying one or more regions of interest within a middle of the consecutive tissue sections. The digital images of the consecutive tissue sections are registered for alignment and the one or more regions of interest are transferred from the image of the middle section to the images of the adjacent sections. Each image of the consecutive tissue sections is then analyzed and scored as appropriate. Using FACTS methods, pathologist time for annotation is reduced to a single slide. Optionally, multiple middle sections may be annotated for regions of interest and transferred accordingly.

摘要翻译： 在连续组织切片（FACTS）上的特征分析包括从组织样本获得多个连续的组织切片，用至少一个生物标志物染色切片，获得其数字图像，以及鉴定所述切片的中间的一个或多个感兴趣区域 连续组织切片。 注册连续组织部分的数字图像以进行对准，并且将一个或多个感兴趣区域从中间部分的图像转移到相邻部分的图像。 然后对连续组织切片的每个图像进行分析并适当评分。 使用FACTS方法，病理学家注释时间缩短到一个幻灯片。 可选地，可以针对感兴趣的区域注释多个中间部分，并相应地传送。