专利检索 ap:"George L. Drusano" 第 1 页

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发明申请
PHARMACEUTICAL COMPOSITIONS CONTAINING PYRROLOQUINOLINE QUINONE AND NEPHROPROTECTANT FOR TREATING ISCHEMIA REPERFUSION INJURIES 审中-公开
标题翻译：含有吡咯烷酮喹诺酮类药物的药物组合物和用于治疗异位再灌注损伤的NEPHROPROTECTANT

公开(公告)号：US20100160367A1

公开(公告)日：2010-06-24

申请号：US12644262

申请日：2009-12-22

申请人： Paul J. Davis , Joel S. Karliner , Shaker A. Mousa , George L. Drusano

发明人： Paul J. Davis , Joel S. Karliner , Shaker A. Mousa , George L. Drusano

IPC分类号： A61K31/4745 , A61P9/10 , A61P13/12

CPC分类号： A61K31/138 , A61K31/437 , A61K31/4745 , A61K2300/00

摘要： The invention includes compositions comprising substantially purified pyrroloquinoline quinone, that are useful in methods for the treatment and prevention of cardiac injury caused by hypoxia or ischemia. The invention also includes methods for the treatment and prevention of cardiac injury comprising contacting a composition of the invention with a human patient.

摘要翻译： 本发明包括包含基本上纯化的吡咯并喹啉醌的组合物，其可用于治疗和预防由缺氧或缺血引起的心脏损伤的方法。本发明还包括治疗和预防心脏损伤的方法，包括将本发明的组合物与人类患者接触。