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公开(公告)号:US20120178742A1
公开(公告)日:2012-07-12
申请号:US13388776
申请日:2010-08-03
申请人: Markus Henrich , Tanja Weil , Mirko Hechenberger , Sibylle Muller , Valerjans Kauss , Ronalds Zemribo , Elina Erdmane , Gints Smits
发明人: Markus Henrich , Tanja Weil , Mirko Hechenberger , Sibylle Muller , Valerjans Kauss , Ronalds Zemribo , Elina Erdmane , Gints Smits
IPC分类号: A61K31/55
CPC分类号: C07D471/04 , C07D487/04 , C07D498/04 , C07D513/04
摘要: The invention relates to heterocyclic derivatives as well as their pharmaceutically acceptable salts. The invention further relates to a process for the preparation of such compounds. The compounds of the invention are mGluR5 modulators and are therefore useful for the control and prevention of acute and/or chronic neurological disorders.
摘要翻译: 本发明涉及杂环衍生物及其药学上可接受的盐。 本发明还涉及制备这些化合物的方法。 本发明的化合物是mGluR5调节剂,因此可用于控制和预防急性和/或慢性神经障碍。