公开(公告)号：US06592853B2

公开(公告)日：2003-07-15

申请号：US09512526

申请日：2000-02-24

申请人： Gregory P. Dodd ,  Kenneth J. Markowitz

发明人： Gregory P. Dodd ,  Kenneth J. Markowitz

IPC分类号： A61K716

CPC分类号： A61K8/21 ,  A61K8/8147 ,  A61Q11/00

摘要： A desensitizing agent for the cleaning and treatment of sensitive teeth in which the essential desensitizing ingredient is a combination of a first desensitizing agent in an amount of about 0.1 to about 2 wt. % of SnF2, and a second desensitizing agent in an amount of about 0.1 to about 20 wt. % of a water soluble or water swellable polyelectrolyte. Dentifrice compositions employing the desensitizing agent of the present invention surprisingly exhibit excellent organoleptic and flavor release properties.

公开(公告)号：US06241972B1

公开(公告)日：2001-06-05

申请号：US09253120

申请日：1999-02-19

申请人： James K. Herms ,  Gregory P. Dodd

发明人： James K. Herms ,  Gregory P. Dodd

IPC分类号： A61K716

CPC分类号： A61K8/25 ,  A61K8/73 ,  A61K8/731 ,  A61K8/8111 ,  A61K8/8164 ,  A61K8/90 ,  A61Q11/00

摘要： A desensitizing agent for the cleaning and treatment of sensitive teeth comprising a copolymer having repeating hydrophobic and hydrophilic regions. Preferred examples include polysoaps such as: a monovalent salt of a hydrolyzed copolymer of an &agr;-olefin and maleic anhydride:, e.g., structually represented as: The copolymer forms micelles in aqueous dispersions such as toothpaste and mouthwash formulations. When applied thereon by brushing or rinsing or other method of application, the copolymers occlude the tubules and seal them off from the external oral environment and thereby alleviate the pain caused by the tooth's sensitivity.

摘要翻译： 用于清洁和处理敏感牙齿的脱敏剂，其包含具有重复疏水和亲水区域的共聚物。 优选的实例包括聚合物，例如：α-烯烃和马来酸酐的水解共聚物的单价盐：例如结构上表示为：共聚物在水性分散体如牙膏和漱口剂制剂中形成胶束。 当通过刷洗或漂洗或其它施用方法在其上施用时，共聚物封闭小管并将其从外部口腔环境中密封，从而减轻由牙齿的敏感性引起的疼痛。