公开(公告)号：US20120022020A1

公开(公告)日：2012-01-26

申请号：US13193977

申请日：2011-07-29

申请人： Guillermo FRANCO RODRÍGUEZ ,  Ibon GUTIERRO ADURIZ

发明人： Guillermo FRANCO RODRÍGUEZ ,  Ibon GUTIERRO ADURIZ

IPC分类号： A61K31/715

CPC分类号： A61K9/2027 ,  A61K9/2072

摘要： A pharmaceutical composition containing a sulfated glycosaminoglycan drug and a polycationic polymer or copolymer wherein the proportion of ammonium groups in the pharmaceutical composition is between 0.01-2.0 μmol ammonium groups/mg pharmaceutical composition, the proportion of glycosaminoglycan in the pharmaceutical form is between 15% to 50% w/w, and the pharmaceutical composition possesses a moisture content of 10% wt or less. A pharmaceutical dosage form containing the pharmaceutical composition, and their use for the treatment of diseases or disorders therapeutically responsive to the glycosaminoglycan.

摘要翻译： 含有硫酸化糖胺聚糖药物和聚阳离子聚合物或共聚物的药物组合物，其中药物组合物中铵基团的比例为0.01-2.0μmol/ mg药物组合物，药物形式中糖胺聚糖的比例为15％至 50％w / w，药物组合物的含水量为10重量％以下。 含有药物组合物的药物剂型及其用于治疗对糖胺聚糖治疗反应的疾病或病症的用途。