公开(公告)号：US07838306B2

公开(公告)日：2010-11-23

申请号：US10380193

申请日：2001-09-14

Applicant: Hanno Baumann ,  Franz-Josef Gerner ,  Michael Hoffmann ,  Roland Horres ,  Andreas Kokott ,  Hans-Peter Leinenbach ,  Gunter Mathar ,  Wolfgang Metzger ,  Veit Otto ,  Walter Ruger ,  Martin Schimmel

Inventor： Hanno Baumann ,  Franz-Josef Gerner ,  Michael Hoffmann ,  Roland Horres ,  Andreas Kokott ,  Hans-Peter Leinenbach ,  Gunter Mathar ,  Wolfgang Metzger ,  Veit Otto ,  Walter Ruger ,  Martin Schimmel

IPC: G01N33/543 ,  G01N33/544

CPC classification number: B01J20/3285 ,  A61M1/3679 ,  B01J20/30 ,  B01J20/321 ,  B01J20/3212 ,  B01J20/3219 ,  B01J20/327 ,  B01J20/3272 ,  B01J20/3282

Abstract: An adsorbent for whole blood in the form of essentially spherical non-aggregated particles. The adsorbent comprises a porous carrier material having an average pore size of ≦1.5 μm, whereby a maximum of 50% of the pore volume may be in pores having a pore size of >1.5 μm, whereby the outer surfaces of the porous carrier material have at least one surface modification M1 so that the outer surface essentially does not interact with blood cells, and the inner surfaces of the porous carrier material, e.g., the surfaces of the pores of the porous carrier material, have at least one surface modification M2 which interacts with substances present in blood.

Abstract translation: 基本上是球形非聚集颗粒形式的全血吸附剂。 该吸附剂包括平均孔径为n1E1.5μm的多孔载体材料，其中孔体积的最大值可以在孔径>1.5μm的孔中，其中多孔载体材料的外表面 具有至少一个表面改性M1，使得外表面基本上不与血细胞相互作用，并且多孔载体材料的内表面（例如多孔载体材料的孔的表面）具有至少一个表面改性M2 其与存在于血液中的物质相互作用。