摘要:
The present invention provides a therapeutically active composition having uricosuric, diuretic and antihypertension properties. The composition contains, as its active ingredient, a tetrazole compound having the structural formula: ##STR1##
A-PROPARGYLAMINOPROPIOPHENONE DERIVATIVES OF THE FORMULA WHEREIN R1 IS (LOWER) ALKYL, (LOWER) ALKENYL, (LOWER) ALKYNYL, BENZYL, CYCLOPROPYL OR CYCLOPROPYLMETHYL AND R2 IS HYDROGEN, (LOWER) ALKYL, PHENYL OR BENZYL; AND THE PHARMACEUTICALLY ACCEPTABLE NONTOXIC SALTS THEREOF EXHIBIT CENTRAL NERVOUS SYSTEM STIMULANT ACTIVITY AND ANOREXIC ACTIVITY AND ARE USEFUL AS CENTRAL NERVOUS SYSTEM STIMUANTS AND TO INHIBIT APPETITE IN MAMMALS.