公开(公告)号：US20070009996A1

公开(公告)日：2007-01-11

申请号：US11166996

申请日：2005-06-24

申请人： Seiichi Matsuda ,  Hala Schepmann

发明人： Seiichi Matsuda ,  Hala Schepmann

IPC分类号： C12P17/00 ,  C12P21/06 ,  C07H21/04 ,  A01H1/00 ,  C07D493/14

CPC分类号： C12N9/1085

摘要： The present invention is directed to nucleic acid sequences of Ginkgo biloba diterpene synthases, particularly of a levopimaradiene synthase. More specifically, the invention is directed to a cell of a unicellular organism, such as Saccharomyces cerevisiae or Escherichia coli, comprising levopimaradiene synthase for the metabolically engineered in vivo biosynthesis of a diterpene and a ginkgolide.

摘要翻译： 本发明涉及银杏叶二萜合成酶，特别是左旋苹果二烯合酶的核酸序列。 更具体地，本发明涉及单细胞生物体例如酿酒酵母或大肠杆菌的细胞，其包含用于二萜和银杏内酯的代谢工程化体内生物合成的左旋丙二烯合酶。