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公开(公告)号:US4994270A
公开(公告)日:1991-02-19
申请号:US179773
申请日:1988-04-11
申请人: LaVerne D. Boeck , David S. Fukuda , Jon S. Mynderse , Marvin M. Hoehn , Ralph E. Kastner , Harold R. Papiska
发明人: LaVerne D. Boeck , David S. Fukuda , Jon S. Mynderse , Marvin M. Hoehn , Ralph E. Kastner , Harold R. Papiska
CPC分类号: C12R1/54 , C07K7/08 , A61K38/00 , Y10S435/896
摘要: New peptide antibiotic A54145, individual A54145 components A, A.sub.1, B, B.sub.1, C, D, E and F and their pharmaceutically acceptable salts, are useful antibacterial agents which also improve growth performance in animals, especially poultry. Biologically pure cultures of the A54145-producing Streptomyces fradiae cultures NRRL 18158, NRRL 18159 and NRRL 18160 cultures and methods of making antibiotic A54145 using those cultures are also provided.
摘要翻译: 新肽抗生素A54145,单独的A54145组分A,A1,B,B1,C,D,E和F及其药学上可接受的盐是可改善动物,特别是家禽生长性能的有用的抗菌剂。 还提供了产生A54145的Streptomyces fradiae培养物NRRL 18158,NRRL 18159和NRRL 18160培养物的生物学纯培养物以及使用这些培养物制备抗生素A54145的方法。