公开(公告)号：US5336495A

公开(公告)日：1994-08-09

申请号：US91885

申请日：1993-07-14

申请人： Desire J. Collen ,  Jean-Marie Stassen ,  Henri R. Lijnen

发明人： Desire J. Collen ,  Jean-Marie Stassen ,  Henri R. Lijnen

IPC分类号： A61K38/16 ,  A61K37/547

CPC分类号： A61K38/164

摘要： The present invention relates to the use of staphylokinase for the preparation of a pharmaceutical composition for treating arterial thrombosis, such as e.g. myocardial infarction. It is demonstrated that staphylokinase can be particularly useful as a thrombolytic agent for the lysis of platelet-rich clots. Furthermore it is demonstrated that staphylokinase, unlike streptokinase, does not induce antibody induction upon repeated administration.

摘要翻译： 本发明涉及葡萄球菌激酶在制备用于治疗动脉血栓形成的药物组合物中的用途， 心肌梗死 证明葡萄球菌激酶可以特别用作裂解血小板富集血块的血栓溶解剂。 此外，证明葡萄球菌激酶与链激酶不同，在重复给药时不诱导抗体诱导。