公开(公告)号：US20070082068A1

公开(公告)日：2007-04-12

申请号：US10579323

申请日：2004-11-17

申请人： Hideo Satsu ,  Tatsumasa Mae ,  Misuzu Tsukagawa ,  Mikio Kitahara ,  Shinichi Yokota ,  Makoto Shimizu

发明人： Hideo Satsu ,  Tatsumasa Mae ,  Misuzu Tsukagawa ,  Mikio Kitahara ,  Shinichi Yokota ,  Makoto Shimizu

IPC分类号： A61K36/185 ,  A61K36/534 ,  A61K31/045 ,  A61K31/015 ,  A61K36/48

CPC分类号： A61K31/045 ,  A23L33/105 ,  A61K31/015 ,  A61K36/185 ,  A61K36/484 ,  A61K36/534

摘要： An object of the present invention is to provide IL-8 production promoters derived from safe food materials and to provide immunostimulants or preventive or treating agents of infectious disease comprising the IL-8 production promoter. The present inventors have found that a composition comprising, as an active ingredient, at least one plant extract from peppermint, dokudami (houttuynia herb), or licorice promotes IL-8 production, and that a composition comprising, as an active ingredient, at least one compound selected from the group consisting of α-humulene, α-pinene, β-pinene, and L-menthol promotes IL-8 production. These IL-8 production promoters can be used in foods and drinks supplemented with immunostimulants or preventive or treating agents of infectious disease.

摘要翻译： 本发明的目的是提供衍生自安全食品材料的IL-8生产促进剂，并提供包含IL-8生产启动子的感染性疾病的免疫刺激剂或预防或治疗剂。 本发明人已经发现，包含作为活性成分的至少一种来自薄荷，dokudami（香草）或甘草的植物提取物的组合物促进IL-8产生，并且包含至少包含作为活性成分的组合物 选自α-葎草酮，α-蒎烯，β-蒎烯和L-薄荷醇的一种化合物促进IL-8的产生。 这些IL-8生产促进剂可用于补充有免疫刺激剂或感染性疾病预防或治疗剂的食品和饮料中。