公开(公告)号：US20120040055A1

公开(公告)日：2012-02-16

申请号：US13266134

申请日：2010-04-13

申请人： Hiroki Ohara ,  Hitoshi Matsumoto ,  Masataka Hata ,  Koichi Terauchi ,  Hidetoshi Nishizawa

发明人： Hiroki Ohara ,  Hitoshi Matsumoto ,  Masataka Hata ,  Koichi Terauchi ,  Hidetoshi Nishizawa

IPC分类号： A23L1/305 ,  A23J1/04 ,  A23J1/10 ,  A23L2/66

CPC分类号： C07K14/78 ,  A23J3/342 ,  A23L2/52 ,  A23L33/18 ,  C07K5/06165 ,  C07K5/0806 ,  C12P21/06 ,  C12Y304/22002

摘要： An object of the present invention is to elucidate a collagen peptide effective for causing dipeptides or tripeptides serving as the active component to enter the blood, and thus to reduce the required intake thereof. According to the present invention, a collagen peptide composition obtained by digesting collagen or gelatin with protease is provided, wherein:(a) the ratio of hydroxyproline to total of amino acid residues at the second position from the N terminus of the peptides in the composition is 2 mol % or more and 20 mol % or less, and the ratio of glycine to total of amino acid residues at the third position from the N terminus of the peptides in the composition is 20 mol % or more and 50 mol % or less; and (b) the average molecular weight is 500 or more and 2000 or less.

摘要翻译： 本发明的目的是阐明有效地引起作为活性成分的二肽或三肽进入血液的胶原肽，从而减少其所需的摄入量。 根据本发明，提供通过用蛋白酶消化胶原蛋白或明胶获得的胶原肽组合物，其中：（a）在组合物中肽的N末端的第二位置处的羟脯氨酸与氨基酸残基的总量的比例 为2摩尔％以上且20摩尔％以下，组合物中的肽的N末端第3位的氨基酸残基的比例为20摩尔％以上且50摩尔％以下 ; 和（b）平均分子量为500以上且2000以下。