公开(公告)号：US4089947A

公开(公告)日：1978-05-16

申请号：US710238

申请日：1976-07-30

申请人： Satoshi Horii ,  Yukihiko Kameda ,  Takashi Iwasa ,  Hiroichi Yamamoto

发明人： Satoshi Horii ,  Yukihiko Kameda ,  Takashi Iwasa ,  Hiroichi Yamamoto

IPC分类号： A01N43/16 ,  C07H15/22 ,  A61K31/71 ,  C07H15/20

CPC分类号： C07H15/22 ,  A01N43/16 ,  Y10S435/898

摘要： Novel antibiotics, termed validamycins C, D, E and F, and acid salts thereof, are prepared by cultivating a validamycin-producing strain of microorganism of the genus Streptomyces, and optionally converting the free base to its acid salt. These antibiotics, as well as validoxylamines A and B, are useful for controlling plant diseases, and can be applied to the plants in the form of the cultured broth, filtrate or concentrate thereof, or purified preparation thereof.

摘要翻译： 称为有效霉素C，D，E和F的新型抗生素及其酸式盐通过培养产生链霉菌属的微生物的有效霉素菌株，并任选地将游离碱转化为其酸盐来制备。 这些抗生素以及有效的甲氧基胺A和B可用于控制植物病害，并且可以以培养的肉汤，滤液或浓缩物或其纯化制剂的形式施用于植物。

公开(公告)号：US4011391A

公开(公告)日：1977-03-08

申请号：US245135

申请日：1972-04-18

申请人： Satoshi Horii ,  Yukihiko Kameda ,  Takashi Iwasa ,  Hiroichi Yamamoto

发明人： Satoshi Horii ,  Yukihiko Kameda ,  Takashi Iwasa ,  Hiroichi Yamamoto

IPC分类号： C07H15/22 ,  C07H15/00

CPC分类号： C07H15/22 ,  Y10S435/898

摘要： Novel antibiotics, termed validamycins C, D, E and F, and acid salts thereof, are prepared by cultivating a validamycin-producing strain of microorganism of the genus Streptomyces, and optionally converting the free base to its acid salt.