公开(公告)号：US3678148A

公开(公告)日：1972-07-18

申请号：US3678148D

申请日：1969-06-26

Applicant: INFORMATION UTILIZATION CORP

Inventor： CAIOLA LEONARD

IPC: G01N1/30 ,  G01T7/08 ,  G02B21/34 ,  A61K27/04 ,  G21H5/02

CPC classification number: G01T7/08 ,  G01N1/30 ,  G02B21/34

Abstract: A slide specimen of exfoliated cells is prepared in the usual manner for microscopic optical examination of a Papanicolaou Test, up to the point of staining. At this stage, instead of the ordinary stains, a stain containing a radioisotope is used. The slide with the radioisotope-bearing stain is thereupon passed through a radiation counter which gives an indication of the amount of radiation the slide emits, which indicates the amount of radioactive stain absorbed by the specimen. This relative absorption amount indicates the differential staining of the cellular material and forms the equivalent electronic differentiation of the specimens to the standard Papanicolaou optical differentiation as viewed through the microscope. In this way, the automatic radiation counter is used to substitute for the human element in the microscopic evaluation of the specimens.

Abstract translation: 以通常的方式制备剥离细胞的载玻片标本，用于Papanicolaou试验的显微镜光学检查，直到染色。 在这个阶段，代替普通污渍，使用含有放射性同位素的污渍。 具有放射性同位素污染物的载玻片随后通过辐射计数器，其给出了载玻片发射的辐射量的指示，其指示由样品吸收的放射性污渍的量。 该相对吸收量表示细胞材料的差异染色，并通过显微镜观察，形成样品与标准Papanicolaou光学分化的等效电子分化。 以这种方式，自动辐射计数器用于在样品的微观评估中代替人体元素。

公开(公告)号：US3801783A

公开(公告)日：1974-04-02

申请号：US3801783D

申请日：1971-07-22

Applicant: INFORMATION UTILIZATION CORP

Inventor： CAIOLA L

IPC: G01N1/30 ,  G01T7/08 ,  G02B21/34 ,  G21H5/02

CPC classification number: G01N1/30 ,  G01T7/08 ,  G02B21/34 ,  Y10S435/808

Abstract: A slide specimen of exfoliated cells is prepared in the usual manner for microscopic optical examination of a Papanicloaou Test, up to the point of staining. At this stage, instead of the ordinary stains, a stain containing a radioisotope is used. The slide with the radioisotope-bearing stain is thereupon passed through a radiation counter which gives an indication of the amount of radiation the slide emits, which indicates the amount of radioactive stain absorbed by the specimen. This relative absorption amount indicates the differential staining of the cellular material and forms the equivalent electronic differentiation of the specimens to the standard Papanicolaou optical differentiation as viewed through the microscope. In this way, the automatic radiation counter is used to substitute for the human element in the microscopic evaluation of the specimens.

Abstract translation: 以通常的方式制备剥离细胞的载玻片标本，以进行Papanicloaou试验的显微镜光学检查，直到染色。 在这个阶段，代替普通污渍，使用含有放射性同位素的污渍。 具有放射性同位素污染物的载玻片随后通过辐射计数器，其给出了载玻片发射的辐射量的指示，其指示由样品吸收的放射性污渍的量。 该相对吸收量表示细胞材料的差异染色，并通过显微镜观察，形成样品与标准Papanicolaou光学分化的等效电子分化。 以这种方式，自动辐射计数器用于在样品的微观评估中代替人体元素。