公开(公告)号：US20240050587A1

公开(公告)日：2024-02-15

申请号：US17766123

申请日：2020-10-01

Applicant: ISTITUTO SCIENTIFICO ROMAGNOLO PER LO STUDIO E LA CURA DEI TUMORI (I.R.S.T.) S.R.L. ,  HOUSTON METHODIST HOSPITAL

Inventor： Alessandro DE VITA ,  Chiara LIVERANI ,  Toni IBRAHIM ,  Laura MERCATALI ,  Ennio TASCIOTTI ,  Roberto MOLINARO

IPC: A61K47/69 ,  C07K16/40 ,  A61K31/704 ,  A61K47/68 ,  A61P35/00

CPC classification number: A61K47/6913 ,  C07K16/40 ,  A61K31/704 ,  A61K47/6855 ,  A61P35/00 ,  C12Y113/11

Abstract: The present invention relates to a liposome comprising a poly(ethylene glycol)-lipid (PEG-lipid), cholesterol and an anti-LOX antibody and relative pharmaceutical formulation, medical uses in particular for the treatment of cancer.

公开(公告)号：US20190117874A1

公开(公告)日：2019-04-25

申请号：US16096466

申请日：2017-04-24

Applicant: Michel RIGAUD ,  ISTITUTO SCIENTIFICO ROMAGNOLO PER LO STUDIO E LA CURA DEI TUMORI (I.R.S.T.) S.R.L

Inventor： Michel RIGAUD ,  Wainer ZOLI ,  Francesco FABBRI ,  Giulia GALLERANI ,  Pietro FICI

IPC: A61M1/36 ,  C07K16/30

Abstract: A device for removing a biological and/or chemical entity (C) from extracorporeal blood (B) is disclosed. The device has a hollow capture chamber with an inlet for the entry of the extracorporeal blood (B) and an outlet for the outflow of the extracorporeal blood (B) and a capture element inside the capture chamber having a reactant surface placed in contact with the extracorporeal blood (B) and a plurality of binding agents (A) for the biological and/or chemical entity to be removed (C) such that the biological and/or chemical entity (C), upon exiting the capture chamber, is removed from the extracorporeal blood (B) as linked to the reactant surface.

公开(公告)号：US11596728B2

公开(公告)日：2023-03-07

申请号：US17099069

申请日：2020-11-16

Applicant: ISTITUTO SCIENTIFICO ROMAGNOLO PER LO STUDIO E LA CURA DEI TUMORI (I.R.S.T.) S.R.L ,  Michel Rigaud

Inventor： Michel Rigaud ,  Wainer Zoli ,  Francesco Fabbri ,  Giulia Gallerani ,  Pietro Fici

IPC: A61M1/36 ,  C07K16/30

Abstract: A device removing a biological and/or chemical entity (C) from extracorporeal blood (B) is disclosed. The device has a hollow capture chamber with an inlet for the entry of the extracorporeal blood (B) and an outlet for the outflow of the extracorporeal blood (B) and a capture element inside the capture chamber having a reactant surface placed in contact with the extracorporeal blood (B) and a plurality of binding agents (A) for the biological and/or chemical entity to be removed (C) such that the biological and/or chemical entity (C), upon exiting the capture chamber, is removed from the extracorporeal blood (B) as linked to the reactant surface.

公开(公告)号：US20210077707A1

公开(公告)日：2021-03-18

申请号：US17099069

申请日：2020-11-16

Applicant: ISTITUTO SCIENTIFICO ROMAGNOLO PER LO STUDIO E LA CURA DEI TUMORI (I.R.S.T.) S.R.L

Inventor： Michel Rigaud ,  Wainer Zoli ,  Francesco Fabbri ,  Giulia Gallerani ,  Pietro Fici

IPC: A61M1/36 ,  C07K16/30

Abstract: A device removing a biological and/or chemical entity (C) from extracorporeal blood (B) is disclosed. The device has a hollow capture chamber with an inlet for the entry of the extracorporeal blood (B) and an outlet for the outflow of the extracorporeal blood (B) and a capture element inside the capture chamber having a reactant surface placed in contact with the extracorporeal blood (B) and a plurality of binding agents (A) for the biological and/or chemical entity to be removed (C) such that the biological and/or chemical entity (C), upon exiting the capture chamber, is removed from the extracorporeal blood (B) as linked to the reactant surface.