Increasing creatine and glycogen concentration in muscle
    4.
    发明授权
    Increasing creatine and glycogen concentration in muscle 失效
    增加肌肉中的肌酸和糖原浓度

    公开(公告)号:US5968900A

    公开(公告)日:1999-10-19

    申请号:US875326

    申请日:1997-09-29

    摘要: Compositions herein increased creatine retention and/or glycogen storage in muscle. A composition comprises creatine or its derivative and a carbohydrate or its derivative. The carbohydrate is in an amount by weight which is greater than the amount of creatine. The amount of carbohydrate and the amount of creatine are effective for increasing creatine retention and/or glycogen storage in muscle. The compositions may be in the form of a pharmaceutical or a dietary supplement and are intended for use in the human or animal body. Other compositions comprise creatine or an active derivative together with insulin or an active derivative. The amount of creatine and the amount of insulin are effective for increasing creatine retention and/or glycogen storage in muscle. The compositions including creatine and insulin may further contain a carbohydrate or its derivative. A method of increasing creatine retention in a human or animal body comprises causing an increase in blood plasma creatine concentration and causing a substantially simultaneous increase in blood plasma insulin concentration. A method of increasing glycogen storage in a human or animal body comprises causing an increase in blood plasma creatine carbohydrate concentration and causing a substantially simultaneous increase in blood plasma creatine concentration. The compositions to increase the creatine retention and/or glycogen storage in the muscle are administered by injection or ingestion.

    摘要翻译: PCT No.PCT / GB95 / 02933 Sec。 371日期:1997年9月29日 102(e)日期1997年9月29日PCT 1995年12月15日PCT PCT。 出版物WO96 / 日期1996年6月20日本文中的组合物增加肌肉中的肌酸保留和/或糖原储存。 组合物包含肌酸或其衍生物和碳水化合物或其衍生物。 碳水化合物的重量含量大于肌酸的量。 碳水化合物的量和肌酸的量对于增加肌肉中的肌酸保留和/或糖原储存是有效的。 组合物可以是药物或膳食补充剂的形式,并且用于人或动物体内。 其它组合物包含肌酸或活性衍生物以及胰岛素或活性衍生物。 肌酸的量和胰岛素的量对于增加肌肉中的肌酸保留和/或糖原储存是有效的。 包含肌酸和胰岛素的组合物还可含有碳水化合物或其衍生物。 增加人或动物体内肌酸保留的方法包括引起血浆肌酸浓度的增加并导致血浆胰岛素浓度基本上同时增加。 增加人或动物体内糖原储存的方法包括引起血浆肌酸碳水化合物浓度的增加并导致血浆肌酸浓度基本上同时增加。 通过注射或摄取来施用增加肌肉中肌酸保留和/或糖原储存的组合物。