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公开(公告)号:US4794107A
公开(公告)日:1988-12-27
申请号:US906653
申请日:1986-09-12
IPC分类号: A61K9/00 , A61K9/06 , A61K31/57 , A61K47/00 , A61P29/00 , A61K31/56 , A61K9/10 , C07J5/00 , C07J7/00
CPC分类号: A61K9/0014 , A61K31/57 , Y10S514/943 , Y10S514/969
摘要: An oily ointment comprising(a) 0.01 to 0.5% by weight of hydrocortisone butyrate propionate,(b) 2 to 10% by weight of a mixture of propylene glycol and purified water in a weight ratio of from 1:5 to 20:1,(c) 0.1 to 6% by weight of a surface-active agent, and(d) 75 to 97% by weight of a higher paraffinic hydrocarbon.
摘要翻译: 一种油性软膏,其包含(a)0.01至0.5重量%的丁酸氢化可的松丙酸酯,(b)2至10重量%的丙二醇与纯化水的混合物,其重量比为1:5至20:1, (c)0.1至6重量%的表面活性剂,和(d)75至97重量%的较高链烷烃。
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公开(公告)号:US4794106A
公开(公告)日:1988-12-27
申请号:US902002
申请日:1986-08-28
CPC分类号: A61K9/0014 , A61K31/57 , A61K9/06 , Y10S514/943 , Y10S514/969
摘要: An oil-in-water type cream comprising(a) 0.01 to 0.5% by weight of hydrocortisone butyrate proponate,(b) 5 to 50% by weight of a higher paraffinic hydrocarbon,(c) 3 to 15% by weight of a surface-active agent,(d) 30 to 65% by weight of purified water,(e) not more than 20% by weight of a monohydric higher alcohol,(f) not more than 20% by weight of a dihdyric or trihydric alcohol, and(g) a pharmaceutically acceptable acid in an amount required to adjust the pH of the cream to a value in the range of 3.5 to 6.5 when it is diluted with water to 20 times its volume.
摘要翻译: 一种水包油型乳膏,其包含(a)0.01至0.5重量%的丙酸氢化可的松酸氢可的松,(b)5至50重量%的较高链烷烃,(c)3至15重量%的表面 活性剂,(d)30〜65重量%的纯水,(e)20重量%以下的一元高级醇,(f)20重量%以下的二羟基或三元醇, 和(g)当将其用水稀释至其体积的20倍时,将膏体的pH调节至3.5至6.5范围内所需的量的药学上可接受的酸。
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