公开(公告)号：US20190201540A1

公开(公告)日：2019-07-04

申请号：US16304020

申请日：2017-05-24

申请人： Bryce Chackerian ,  Alan Remaley ,  Ingrid Lindquist ,  Ingrid Lindquist ,  STC UNM

发明人： Bryce Chackerian ,  Alan Ramaley ,  Ingrid Lindquist

IPC分类号： A61K47/64 ,  A61K39/00 ,  A61K39/12 ,  A61K47/69 ,  C07K14/775 ,  A61P3/06 ,  C12N15/85

CPC分类号： A61K47/646 ,  A61K39/0005 ,  A61K39/12 ,  A61K45/06 ,  A61K47/6901 ,  A61K2039/62 ,  A61P3/06 ,  C07K14/775 ,  C12N15/85 ,  C12N2795/18123

摘要： This disclosure describes immunogens, compositions, and methods for treating dyslipidemia. The immunogen included an ApoC3-derived peptide linked to a bacteriophage virus like particle (VLP) immunogenic carrier. The ApoC3 immunogen can be administered to a subject having, or at risk of having, dyslipidemia. The ApoC3 immunogen may be administered alone or co-administered with an additional dyslipidemia therapeutic agent.