公开(公告)号：US20160059042A1

公开(公告)日：2016-03-03

申请号：US14834059

申请日：2015-08-24

Applicant: Ion Beam Applications S.A. ,  Instituto Nazionale di Fisica Nucleare ,  Internet-Simulation Evaluation Envision SRL

Inventor： Germano Russo ,  Andrea Attili ,  Flavio Pietro Marchetto ,  Damien Bertrand ,  Faiza Bourhaleb

IPC: A61N5/10

CPC classification number: A61N5/1075 ,  A61N5/1031 ,  A61N5/1043 ,  A61N2005/1076 ,  A61N2005/1087

Abstract: The method of the invention comprises the steps of: providing a reference ion beamlet; determining in a phantom (60) a distribution of a linearly-superposable quantity representing a linearly-superposable effect induced by said reference ion beamlet; approximating an ion beam (10) as a weighted superposition of ion beamlets (15), said weighted superposition comprising weight coefficients, at least one ion beamlet (15) being obtained by applying a roto-translation operation to said reference ion beamlet; determining a roto-translated distribution of a linearly-superposable quantity by roto-translating said distribution of a linearly-superposable quantity with said roto-translation operation; determining said physical and/or radiobiological quantities by performing a weighted superposition comprising said weight coefficients, and said roto-translated distribution of a linearly-superposable quantity.

Abstract translation: 本发明的方法包括以下步骤：提供参考离子束; 在虚部（60）中确定表示由所述参考离子束引起的线性叠加效应的线性叠加量的分布; 将离子束（10）近似为离子束（15）的加权叠加，所述加权叠加包括权重系数，至少一个离子束（15）通过向所述参考离子束施加旋转平移操作而获得; 通过利用所述转换操作旋转所述线性叠加量的分布来确定线性叠加量的旋转翻译分布; 通过执行包括所述权重系数的加权叠加以及线性叠加量的所述旋转翻译分布来确定所述物理和/或放射生物量。

公开(公告)号：US09878181B2

公开(公告)日：2018-01-30

申请号：US14834059

申请日：2015-08-24

Applicant: Ion Beam Applications S.A. ,  Instituto Nazionale di Fisica Nucleare ,  Internet-Simulation Evaluation Envision SRL

Inventor： Germano Russo ,  Andrea Attili ,  Flavio Pietro Marchetto ,  Damien Bertrand ,  Faiza Bourhaleb

IPC: A61N5/10

CPC classification number: A61N5/1075 ,  A61N5/1031 ,  A61N5/1043 ,  A61N2005/1076 ,  A61N2005/1087

Abstract: The method of the invention comprises the steps of: providing a reference ion beamlet; determining in a phantom (60) a distribution of a linearly-superposable quantity representing a linearly-superposable effect induced by said reference ion beamlet; approximating an ion beam (10) as a weighted superposition of ion beamlets (15), said weighted superposition comprising weight coefficients, at least one ion beamlet (15) being obtained by applying a roto-translation operation to said reference ion beamlet; determining a roto-translated distribution of a linearly-superposable quantity by roto-translating said distribution of a linearly-superposable quantity with said roto-translation operation; determining said physical and/or radiobiological quantities by performing a weighted superposition comprising said weight coefficients, and said roto-translated distribution of a linearly-superposable quantity.