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公开(公告)号:US08530493B2
公开(公告)日:2013-09-10
申请号:US12280424
申请日:2007-02-21
IPC分类号: A61K31/435 , A61K31/44 , A61K31/41 , A61K31/40
CPC分类号: C07D471/14
摘要: Compounds of a certain formula I, in which R1, R2, R3, R4, R5 and R6 have the meanings indicated in the description, are effective compounds with anti-proliferative and/or apoptosis inducing activity.
摘要翻译: 其中R1,R2,R3,R4,R5和R6具有说明书中所示含义的某种式I化合物是具有抗增殖和/或凋亡诱导活性的有效化合物。
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公开(公告)号:US20090246169A1
公开(公告)日:2009-10-01
申请号:US12280264
申请日:2007-02-21
IPC分类号: A61K38/20 , C07D471/12 , A61K31/437 , C07D401/14 , A61K31/496 , C07D413/14 , A61K31/5377 , A61K31/55 , A61K31/397 , A61P35/00
CPC分类号: C07D471/14
摘要: Compounds of a certain formula I, in which R1, R2, R3, R4, R5 and R6 have the meanings indicated in the description, are effective compounds with anti-proliferative and/or apoptosis inducing activity.
摘要翻译: 其中R1,R2,R3,R4,R5和R6具有说明书中所示含义的某种式I化合物是具有抗增殖和/或凋亡诱导活性的有效化合物。
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公开(公告)号:US07718665B2
公开(公告)日:2010-05-18
申请号:US11659738
申请日:2005-08-17
申请人: Matthias Vennemann , Thomas Baer , Gudrun Groegor , Jürgen Braunger , Petra Gimmnich , Thomas Maier , Heike Rothfels
发明人: Matthias Vennemann , Thomas Baer , Gudrun Groegor , Jürgen Braunger , Petra Gimmnich , Thomas Maier , Heike Rothfels
IPC分类号: C07D495/14 , A61K31/437 , A61P35/00
CPC分类号: C07D471/14 , C07D495/14
摘要: Compounds of the formula (1) in which R1, R2, R3, R4 and X have the meanings indicated in the description, are novel effective compounds with Eg5 inhibitory, anti-proliferative and/or apoptosis inducing activity.
摘要翻译: 其中R1,R2,R3,R4和X具有说明书中所示含义的式(1)化合物是具有Eg5抑制,抗增殖和/或凋亡诱导活性的新型有效化合物。
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公开(公告)号:US20090233902A1
公开(公告)日:2009-09-17
申请号:US12280424
申请日:2007-02-21
IPC分类号: A61K31/437 , C07D471/14 , A61K31/55 , A61P35/00
CPC分类号: C07D471/14
摘要: Compounds of a certain formula I, in which R1, R2, R3, R4, R5 and R6 have the meanings indicated in the description, are effective compounds with anti-proliferative and/or apoptosis inducing activity.
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公开(公告)号:US20100104659A1
公开(公告)日:2010-04-29
申请号:US12373433
申请日:2007-07-12
申请人: Matthias Vennemann , Thomas Bär , Thomas Maier , Andreas Lindenmaier , Jürgen Braunger , Markus Boehm , Astrid Zimmermann , Volker Gekeler
发明人: Matthias Vennemann , Thomas Bär , Thomas Maier , Andreas Lindenmaier , Jürgen Braunger , Markus Boehm , Astrid Zimmermann , Volker Gekeler
IPC分类号: A61K31/4162 , C07D491/04 , C07D471/02 , C07D401/14 , C07D403/14 , A61K31/4738 , A61K31/454 , A61K31/496 , A61K33/24 , A61P35/00 , A61K31/397
CPC分类号: C07D491/04
摘要: Compounds of a certain formula I, in which Ra, Rb and Rc have the meanings indicated in the description, are effective compounds with anti-proliferative and/or apoptosis inducing activity.
摘要翻译: 其中Ra,Rb和Rc具有说明书中所示含义的某种式I化合物是具有抗增殖和/或凋亡诱导活性的有效化合物。
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