公开(公告)号：US07022503B2

公开(公告)日：2006-04-04

申请号：US10238308

申请日：2002-09-09

申请人： Christian Wandrey ,  Murillo De Oliveira Villela Filho ,  Andreas Liese ,  Jan A. M. De Bont ,  Jan C. Verdoes ,  Carel A. G. M. Weijers ,  J. Hans Visser ,  Claus Dreisbach

发明人： Christian Wandrey ,  Murillo De Oliveira Villela Filho ,  Andreas Liese ,  Jan A. M. De Bont ,  Jan C. Verdoes ,  Carel A. G. M. Weijers ,  J. Hans Visser ,  Claus Dreisbach

IPC分类号： C12P7/44 ,  C12P7/46 ,  C12N9/16

CPC分类号： C12P7/42 ,  C12P7/62 ,  C12P17/02

摘要： The present invention relates to a process for the kinetic resolution of racemic functionalized epoxides in the presence of microorganisms, crude or pure preparations thereof comprising a polypeptide having epoxide hydrolase activity. Preferred microorganisms are yeasts and bacteria which may also be recombinant.