公开(公告)号：US07144991B2

公开(公告)日：2006-12-05

申请号：US10013173

申请日：2001-12-07

Applicant: Stephen Charles Goshorn ,  Scott Stoll Graves ,  Joanne Elaine Schultz ,  Yukang Lin ,  James Allen Sanderson ,  John M. Reno

Inventor： Stephen Charles Goshorn ,  Scott Stoll Graves ,  Joanne Elaine Schultz ,  Yukang Lin ,  James Allen Sanderson ,  John M. Reno

IPC: C07K16/46

CPC classification number: B82Y5/00 ,  A61K39/00 ,  A61K47/665 ,  C07K14/36 ,  C07K16/2896 ,  C07K2317/622 ,  C07K2319/00 ,  C07K2319/02 ,  C07K2319/22

Abstract: The present invention provides vectors for expressing genomic streptavidin fusion cassettes. In the various embodiments, fusion proteins produced from these vectors are provided. In particular embodiments, fusion proteins comprising a single chain antibody and genomic streptavidin are provided as are vectors encoding the same. Also provided, are methods of using the fusion proteins of the present invention, and in particular, the use of scFvSA fusion proteins as diagnostic markers or as a cell specific targeting agents.

公开(公告)号：US4012286A

公开(公告)日：1977-03-15

申请号：US675389

申请日：1976-04-09

Applicant: James Allen Sanderson ,  William S. Stavropoulos

Inventor： James Allen Sanderson ,  William S. Stavropoulos

IPC: C12Q1/50 ,  G01N31/14 ,  G01N33/00

CPC classification number: C12Q1/50

Abstract: An improved method and compositions useful for determining the creatine phosphokinase activity of body fluids suitable for use on clinical colorimeters which involves pre-activation of the creatine phosphokinase with a novel pre-activation composition and comparison to a chemical standard.

Abstract translation: 一种改进的方法和组合物，其可用于测定适用于临床色度计的体液的肌酸磷酸激酶活性，其包括用新的预活化组合物预先激活肌酸磷酸激酶并与化学标准进行比较。