公开(公告)号：US07053065B2

公开(公告)日：2006-05-30

申请号：US10297821

申请日：2001-06-15

Applicant: Clet Niyikiza ,  Paolo Paoletti ,  James Jacob Rusthoven

Inventor： Clet Niyikiza ,  Paolo Paoletti ,  James Jacob Rusthoven

IPC: A01N43/04 ,  A61K31/70

CPC classification number: A61K31/525 ,  A61K31/519 ,  A61K31/70 ,  A61K31/714 ,  A61K2300/00

Abstract: A method of administering an antifolate to a mammal in need thereof, comprising administering an effective amount of said antifolate in combination with a methylmalonic acid lowering agent.

Abstract translation: 向有需要的哺乳动物施用抗叶酸剂的方法，包括与甲基丙二酸降解剂组合施用有效量的所述抗叶酸剂。