-
公开(公告)号:US20150258211A1
公开(公告)日:2015-09-17
申请号:US14405701
申请日:2013-06-06
申请人: Jamie Rayahin , Jason Buhrman , Richard Gemeinhart , The Board of Trustees of the University of Illinois
发明人: Richard Gemeinhart , Jason Buhrman , Jamie Rayahin
CPC分类号: A61K47/48784 , A61K9/06 , A61K38/00 , A61K47/32 , A61K47/48215 , A61K47/60 , A61K47/6903 , A61K49/0047 , A61K49/0091
摘要: Disclosed herein is a hydrogel composition comprising a polymer covalently linked to glutathione (GSH). Also disclosed herein is a method for providing localized delivery of one or more agents in a subject suffering from a disease. The method comprises administering to the subject a GST/GSH affinity hydrogel comprising a therapeutically effective amount of the one or more agents.
摘要翻译: 本文公开了包含共价连接到谷胱甘肽(GSH)的聚合物的水凝胶组合物。 本文还公开了一种在患有疾病的受试者中提供一种或多种药剂的局部递送的方法。 该方法包括向受试者施用包含治疗有效量的一种或多种试剂的GST / GSH亲和性水凝胶。