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    Methods of reducing serum glucose and triglyceride levels and for inhibiting angiogenesis using substituted indolealkanoic acids
    1.
    发明授权
    Methods of reducing serum glucose and triglyceride levels and for inhibiting angiogenesis using substituted indolealkanoic acids 失效
    降低血清葡萄糖和甘油三酯水平以及用取代的吲哚烷酸抑制血管发生的方法

    公开(公告)号：US06555568B1

    公开(公告)日：2003-04-29

    申请号：US09452252

    申请日：1999-12-01

    申请人： Janet Sredy ,  Jorge Jacot

    发明人： Janet Sredy ,  Jorge Jacot

    IPC分类号： A61K31405

    CPC分类号： A61K31/428 ,  A61K31/405 ,  A61K31/427 ,  A61K31/4439

    摘要： Disclosed are methods of reducing serum glucose and triglyceride levels and for inhibiting angiogenesis, the methods comprising administration of substituted indolealkanoic acids to patients in need of such treatment. Also disclosed are such compounds useful in the treatment of angiogenesis, hyperglycemia, hyperlipidemia and chronic complications arising from diabetes mellitus. Also disclosed are pharmaceutical compositions containing the compounds.

    摘要翻译： 公开了减少血清葡萄糖和甘油三酯水平和抑制血管发生的方法，所述方法包括向需要这种治疗的患者施用取代的吲哚烷酸。 还公开了可用于治疗血糖发生，高血糖症，高脂血症和由糖尿病引起的慢性并发症的化合物。 还公开了含有这些化合物的药物组合物。

    Methods of Reducing Serum Glucose and Triglyceride Levels and for Inhibiting Angiogenesis Using Substituted Indolealkanoic Acids
    3.
    发明申请
    Methods of Reducing Serum Glucose and Triglyceride Levels and for Inhibiting Angiogenesis Using Substituted Indolealkanoic Acids 审中-公开
    使用取代的吲哚烷酸降低血清葡萄糖和甘油三酯水平并抑制血管生成的方法

    公开(公告)号：US20120065203A1

    公开(公告)日：2012-03-15

    申请号：US13302906

    申请日：2011-11-22

    申请人： Janet Sredy ,  Jorge Jacot

    发明人： Janet Sredy ,  Jorge Jacot

    IPC分类号： A61K31/5377 ,  A61P3/10 ,  A61P43/00 ,  A61K31/428 ,  A61P3/06

    CPC分类号： A61K31/428 ,  A61K31/405 ,  A61K31/427 ,  A61K31/4439

    摘要： Disclosed are methods of reducing serum glucose and triglyceride levels and for inhibiting angiogenesis, the methods comprising administration of substituted indolealkanoic acids to patients in need of such treatment. Also disclosed are such compounds useful in the treatment of angiogenesis, hyperglycemia, hyperlipidemia and chronic complications arising from diabetes mellitus. Also disclosed are pharmaceutical compositions containing the compounds.

    摘要翻译： 公开了减少血清葡萄糖和甘油三酯水平和抑制血管发生的方法，所述方法包括向需要这种治疗的患者施用取代的吲哚烷酸。 还公开了可用于治疗血糖发生，高血糖症，高脂血症和由糖尿病引起的慢性并发症的化合物。 还公开了含有这些化合物的药物组合物。

    Compositions containing a substituted indolealkanoic acid and an angiotensin converting enzyme inhibitor
    6.
    发明授权
    Compositions containing a substituted indolealkanoic acid and an angiotensin converting enzyme inhibitor 失效
    含有取代的吲哚烷酸和血管紧张素转换酶抑制剂的组合物

    公开(公告)号：US06521659B2

    公开(公告)日：2003-02-18

    申请号：US09795161

    申请日：2001-02-28

    申请人： Janet Sredy ,  Michael C. Van Zandt

    发明人： Janet Sredy ,  Michael C. Van Zandt

    IPC分类号： A61K3140

    CPC分类号： A61K31/404 ,  A61K31/401 ,  A61K45/06 ,  A61K2300/00

    摘要： Disclosed are methods of reducing serum glucose and triglyceride levels and for inhibiting angiogenesis, the methods comprising administration of substituted indolealkanoic acids to patients in need of such treatment. Also disclosed are such compounds useful in the treatment of angiogenesis, hyperglycemia, hyperlipidemia and chronic complications arising from diabetes mellitus. Also disclosed are pharmaceutical compositions containing the compounds. Further, disclosed are combinations of an angiotensin converting enzyme inhibitor and a substituted indole acetic acid.

    摘要翻译： 公开了降低血清葡萄糖和甘油三酯水平和抑制血管发生的方法，所述方法包括向需要这种治疗的患者施用取代的吲哚烷酸。 还公开了可用于治疗血糖发生，高血糖症，高脂血症和由糖尿病引起的慢性并发症的化合物。 还公开了含有这些化合物的药物组合物。 此外，公开了血管紧张素转换酶抑制剂和取代的吲哚乙酸的组合。