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3 条记录 (耗时 0.009 秒)

    Continuous direct preparation of nitrophenols
    2.
    发明授权
    Continuous direct preparation of nitrophenols 失效
    连续直接制备硝基酚

    公开(公告)号：US5030769A

    公开(公告)日：1991-07-09

    申请号：US432498

    申请日：1989-11-07

    申请人： Michel Baudouin ,  Jean-Luc Bougeois ,  Serge Ratton ,  Jean-Pierre Lecouve

    发明人： Michel Baudouin ,  Jean-Luc Bougeois ,  Serge Ratton ,  Jean-Pierre Lecouve

    IPC分类号： C07C201/08 ,  C07C205/22

    CPC分类号： C07C201/08

    摘要： Nitrophenols, in an isomer ratio para-nitrophenol/ortho-nitrophenol of at least 55/45, are continuously and directly prepared in steady state, by (a) establishing, in a confined reaction zone, an aqueous reaction solution including from 5% to 40% by weight of nitric acid, from 5% to 40% by weight of nitrous acid relative thereto, and an amount of nitrophenols within the limits of the solubility thereof in such reaction solution, (b) continuously introducing and reacting phenol and nitric acid into and with such reaction solution, at a rate of about 0.5 to 2.0 moles of nitric acid per mole of phenol, (c) maintaining the temperature in such confined reaction zone at a value ranging from about 10.degree. to about 40.degree. C. during such reaction, and (d) continuously withdrawing from such confined reaction zone admixture of para-nitrophenol and ortho-nitrophenol, in an isomer ratio para-nitrophenol/ortho-nitrophenol of at least 55/45.

    摘要翻译： 至少55/45的异构体对硝基苯酚/邻硝基苯酚的硝基苯酚以稳定状态连续并直接制备，通过（a）在约束反应区中建立包含5％至 40重量％的硝酸，相对于其的亚硝酸的5〜40重量％，以及在该反应溶液中溶解度范围内的硝基酚的量，（b）连续引入和反应苯酚和硝酸 以每摩尔苯酚约0.5至2.0摩尔硝酸的速率进入和与该反应溶液反应，（c）将该限制反应区中的温度保持在约10℃至约40℃的温度范围内 这样的反应，和（d）以至少55/45的对硝基苯酚/邻硝基苯酚的异构体比例连续地从对硝基苯酚和邻硝基苯酚的限制反应区混合物中排出。

    Bromination of substituted benzaldehydes
    3.
    发明授权
    Bromination of substituted benzaldehydes 失效
    取代的苯甲醛的溴化

    公开(公告)号：US4551558A

    公开(公告)日：1985-11-05

    申请号：US685373

    申请日：1984-12-24

    申请人： Serge Ratton ,  Jean-Luc Bougeois

    发明人： Serge Ratton ,  Jean-Luc Bougeois

    IPC分类号： C07C45/00 ,  C07C45/63 ,  C07C47/565 ,  C07C47/57 ,  C07C47/575 ,  C07C67/00

    CPC分类号： C07C47/565 ,  C07C45/63 ,  C07C47/575

    摘要： Substituted bromobenzaldehydes, e.g., 5-bromovanillin, are facilely prepared with overall avoidance of HBr by-product, by (i) first brominating the corresponding benzaldehyde with a less than stoichiometric amount of bromine, and (ii) completing said bromination reaction with a brominating couple which comprises (1) the hydrobromic acid generated in situ in the step (i) and (2) a bromide ion oxidizer.

    摘要翻译： 通过（i）用小于化学计量的溴首先溴化相应的苯甲醛，和（ii）用溴化物完成所述溴化反应，容易地制备取代的溴苯甲醛，例如5-溴代氨苄青霉素，总体上避免了HBr副产物 其包括（1）在步骤（i）和（2）中原位产生的溴溴酸溴离子氧化剂。