公开(公告)号：US20100028968A1

公开(公告)日：2010-02-04

申请号：US12300958

申请日：2007-05-17

申请人： Clinton Rubin ,  Stefan Judex ,  Jeff Pessin

发明人： Clinton Rubin ,  Stefan Judex ,  Jeff Pessin

IPC分类号： C12N13/00

CPC分类号： A61H23/02 ,  A61H1/005 ,  A61H2201/0142 ,  A61H2201/0149 ,  A61H2203/0406 ,  A61H2203/0425 ,  A61H2203/0456 ,  C12N13/00

摘要： Methods of maintaining or improving the metabolic state of a subject, e.g., a human, are disclosed. The methods can include providing to the subject a low magnitude, high frequency mechanical signal on a periodic basis and for a time sufficient to maintain or improve the subject's metabolic state. The subject can be diagnosed as having or can be at risk of developing, an obesity-related medical condition, e.g., type 2 diabetes, cardiovascular disease, hypertension, rheumatoid arthritis, and breast cancer. The methods can include a step of identifying a suitable subject by evaluating a physiological parameter that reflects the metabolic state of the subject, e.g., visceral fat content, subcutaneous fat content, body mass index, and blood pressure.

摘要翻译： 公开了维持或改善受试者例如人的代谢状态的方法。 所述方法可以包括向患者提供周期性基础上的低幅度高频机械信号，并且足以维持或改善受试者的代谢状态的时间。 可以将该受试者诊断为具有或可能处于与肥胖有关的疾病如II型糖尿病，心血管疾病，高血压，类风湿性关节炎和乳腺癌的风险中。 所述方法可以包括通过评估反映受试者的代谢状态的生理参数，例如内脏脂肪含量，皮下脂肪含量，体重指数和血压来鉴定合适受试者的步骤。