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公开(公告)号:US20120214181A1
公开(公告)日:2012-08-23
申请号:US13466418
申请日:2012-05-08
申请人: Brian M. Beyer , Thomas Hesson , Hung V. Le , Andrew J. Prongay , Krishna Kalghatgi , Jennifer Joanne Gesell , Richard N. Ingram , Michael R. Ziebell
发明人: Brian M. Beyer , Thomas Hesson , Hung V. Le , Andrew J. Prongay , Krishna Kalghatgi , Jennifer Joanne Gesell , Richard N. Ingram , Michael R. Ziebell
IPC分类号: C12Q1/37 , G01N33/53 , G01N27/62 , G01N27/447 , G01N30/00
CPC分类号: C12Q1/37 , G01N2333/96433 , G01N2500/04 , G01N2800/044
摘要: The present invention provides methods for identifying modulators of PCSK9, for example, using a variety of assay formats. Inhibitors of PCSK9 can be used for example, to treat diseases such as hyperlipidemia and related disorders.
摘要翻译: 本发明提供了用于鉴定PCSK9调节剂的方法,例如使用多种测定形式。 PCSK9的抑制剂可用于例如治疗诸如高脂血症和相关疾病的疾病。
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公开(公告)号:US08206943B1
公开(公告)日:2012-06-26
申请号:US12493752
申请日:2009-06-29
申请人: Brian M. Beyer , Thomas Hesson , Hung V. Le , Andrew J. Prongay , Krishna Kalghatgi , Jennifer Joanne Gesell , Richard N. Ingram , Michael R. Ziebell
发明人: Brian M. Beyer , Thomas Hesson , Hung V. Le , Andrew J. Prongay , Krishna Kalghatgi , Jennifer Joanne Gesell , Richard N. Ingram , Michael R. Ziebell
IPC分类号: C12Q1/37
CPC分类号: C12Q1/37 , G01N2333/96433 , G01N2500/04 , G01N2800/044
摘要: The present invention provides methods for identifying modulators of PCSK9, for example, using a variety of assay formats. Inhibitors of PCSK9 can be used for example, to treat diseases such as hyperlipidemia and related disorders.
摘要翻译: 本发明提供了用于鉴定PCSK9调节剂的方法,例如使用多种测定形式。 PCSK9的抑制剂可用于例如治疗诸如高脂血症和相关疾病的疾病。
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