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    Transdermal delivery system of diclofenac with improved water absorbability and adhesion properties
    1.
    发明授权
    Transdermal delivery system of diclofenac with improved water absorbability and adhesion properties 有权
    双氯芬酸的透皮递送系统具有改善的吸水性和粘附性能

    公开(公告)号：US07691404B2

    公开(公告)日：2010-04-06

    申请号：US10415628

    申请日：2001-11-05

    申请人： Jin Deog Song ,  Dong-Won Kim

    发明人： Jin Deog Song ,  Dong-Won Kim

    IPC分类号： A61F13/02 ,  A61L15/16 ,  A61F13/00

    CPC分类号： A61K9/7053 ,  A61K9/7061 ,  A61K31/196 ,  A61K47/02 ,  A61K47/32

    摘要： An active agent containing adhesive composition suitable for transdermal drug delivery having excellent water absorbability which comprises an effective amount of an active agent, an acrylate adhesive, a polyvinylpyrrolidone having a molecular weight of 1,000,000-5,000,000; a polyvinylpyrrolidone having a molecular weight of 2,000-50,000; a non-ionic surfactant; a terpene; and a dissolution assistant.

    摘要翻译： 含有适用于透皮药物递送的粘合剂组合物的活性剂，其具有优异的吸水性，其包含有效量的活性剂，丙烯酸酯粘合剂，分子量为1,000,000-5,000,000的聚乙烯吡咯烷酮; 分子量为2,000〜5000的聚乙烯吡咯烷酮; 非离子表面活性剂; 萜烯 和解散助理。

    Transdermal composition of an antivomiting agent
    2.
    发明授权
    Transdermal composition of an antivomiting agent 有权
    抗病毒剂的透皮组合物

    公开(公告)号：US07273619B2

    公开(公告)日：2007-09-25

    申请号：US10414827

    申请日：2003-04-15

    申请人： Chaul Min Pai ,  Jin Deog Song ,  Joong Woong Cho

    发明人： Chaul Min Pai ,  Jin Deog Song ,  Joong Woong Cho

    IPC分类号： A61F13/00 ,  A61F15/16

    CPC分类号： A61K9/0014 ,  A61K9/7023 ,  A61K31/00 ,  A61K31/46 ,  A61K47/10 ,  A61K47/14 ,  A61K47/18 ,  A61K47/38

    摘要： The present invention relates to a transdermal composition of an antivomiting agent, and more particularly to a transdermal composition of an antivomiting agent which can minimize skin irritation by employing tropisetron as the antivomiting agent as well as by adjusting its pH to be in the range of 8 to 9 thus enhancing its rate of skin penetration thereby reducing the amount of a skin penetration enhancer used.

    摘要翻译： 本发明涉及抗病毒剂的透皮组合物，更具体地说，涉及一种抗病毒剂的透皮组合物，其可以通过使用托烷司琼作为抗病毒剂，并通过将其pH调节至8范围内来最小化皮肤刺激 从而提高其皮肤渗透速率，从而减少使用的皮肤渗透增强剂的量。

    Transdermal drug delivery system for anti-inflammatory analgesic agent comprising diclofenac diethylammonium salt, and the manufacturing method thereof
    3.
    发明授权
    Transdermal drug delivery system for anti-inflammatory analgesic agent comprising diclofenac diethylammonium salt, and the manufacturing method thereof 有权
    包含双氯芬酸二乙基铵盐的消炎止痛剂的透皮给药系统及其制造方法

    公开(公告)号：US06723337B1

    公开(公告)日：2004-04-20

    申请号：US09509303

    申请日：2000-06-19

    申请人： Jin Deog Song ,  Chul Min Park ,  Young Kwon Choi ,  Heon Han Lee ,  Yong Ho Shim ,  Hye Jeong Yoon

    发明人： Jin Deog Song ,  Chul Min Park ,  Young Kwon Choi ,  Heon Han Lee ,  Yong Ho Shim ,  Hye Jeong Yoon

    IPC分类号： A61F1302

    CPC分类号： A61K9/703 ,  A61K9/7061 ,  A61K31/196 ,  Y10S514/946 ,  Y10S514/947 ,  Y10S514/964

    摘要： The invention herein relates to a transdermal drug delivery systern for anti-Inflammatory analgesic. agent comprising diclofenac diethylammonium salt, wherein a backing film (1), a matrix layer (2) containing active ingredients, a release liner (3) which is removed before application onto the skin are laminated therein. Mome particularly, the invention herein relates to a transdermal drug delivery system for anti-inflammatory analgesic agent comprising diclofenac diethylammonum salt, wherein the transdermal penetration and adhesion of the patch to the body are enhanced by means of a matrix layer which comprises a diclofenac diethylammonum salt as active ingredient in addition to acrylic polymer as adhesive constituent, non-ionic surfacant as absorption enhancer, terpene and dissolution assistant, and the volatile and non-volatile constituents of the composition arc separately applied therein for significantly reducing the manufacturing time thereof.

    摘要翻译： 本发明涉及用于抗炎镇痛剂的透皮药物递送系统。 包含双氯芬酸二乙基铵盐的药剂，其中背衬膜（1），含有活性成分的基质层（2），在施用于皮肤之前被去除的剥离衬垫（3）。 特别地，本发明涉及用于消炎止痛剂的透皮药物递送系统，其包括双氯芬酸二乙基铵盐，其中通过包含双氯芬酸二乙基铵盐的基质层增强贴片对身体的透皮渗透和粘附 作为除了作为粘合剂成分的丙烯酸类聚合物之外的活性成分，作为吸收促进剂的非离子表面活性剂，萜烯和溶解助剂以及组合物的挥发性和非挥发性组分分别施加在其中，以显着减少其制造时间。