公开(公告)号：US20150329529A1

公开(公告)日：2015-11-19

申请号：US14711684

申请日：2015-05-13

Applicant: Kamlesh Jagdis BALA ,  Andrew BEARLEY ,  James DALE ,  Anne-Marie EDWARDS ,  Mahbub AHMED ,  David PORTER ,  Robert Alexander PULZ ,  Lisa Ann ROONEY ,  David Andrew SANDHAM ,  Duncan SHAW ,  Nicole SMITH ,  Jessica Louise TAYLOR ,  Roger John TAYLOR ,  Thomas Josef Troxler ,  Joe WRIGGLESWORTH

Inventor： Kamlesh Jagdis BALA ,  Andrew BEARLEY ,  James DALE ,  Anne-Marie EDWARDS ,  Mahbub AHMED ,  David PORTER ,  Robert Alexander PULZ ,  Lisa Ann ROONEY ,  David Andrew SANDHAM ,  Duncan SHAW ,  Nicole SMITH ,  Jessica Louise TAYLOR ,  Roger John TAYLOR ,  Thomas Josef Troxler ,  Joe WRIGGLESWORTH

IPC: C07D413/12 ,  C07D413/14 ,  A61K31/422

CPC classification number: A61K31/422 ,  A61K31/4155 ,  C07D413/12 ,  C07D413/14 ,  A61K2300/00

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract translation: 本发明提供式（I）化合物或其药学上可接受的盐; 制备本发明化合物的方法及其治疗用途。 本发明还提供药理活性剂和药物组合物的组合。