公开(公告)号：US20060286570A1

公开(公告)日：2006-12-21

申请号：US11372485

申请日：2006-03-09

申请人： Kathy Rowlen ,  John Birks ,  Christopher Bowman ,  Hadley Sikes ,  Ryan Hansen ,  Robert Kuchta

发明人： Kathy Rowlen ,  John Birks ,  Christopher Bowman ,  Hadley Sikes ,  Ryan Hansen ,  Robert Kuchta

IPC分类号： C12Q1/70 ,  C12Q1/68

CPC分类号： C12Q1/6816 ,  C12Q2565/401

摘要： The invention provides methods to detect molecular recognition events. The invention also provides methods to detect the presence of or identify a target species based on its interaction with one or more probe species. The methods of the invention are based on amplification of the signal due to each molecular recognition event. The amplification is achieved through photopolymerization, with the polymer formed being associated with the molecular recognition event. In an embodiment, a fluorescent polymer, a magnetic polymer, a radioactive polymer or an electrically conducting polymer can form the basis of detection and amplification. In another embodiment, a polymer gel swollen with a fluorescent solution, a magnetic solution, a radioactive solution or an electrically conducting solution can form the basis of detection and amplification. In another embodiment, sufficient polymer forms to be detectable by visual inspection.

摘要翻译： 本发明提供检测分子识别事件的方法。 本发明还提供了基于其与一种或多种探针物种的相互作用来检测靶物种的存在或鉴定目的物种的方法。 本发明的方法基于由于每个分子识别事件引起的信号的放大。 通过光聚合实现扩增，形成的聚合物与分子识别事件相关联。 在一个实施方案中，荧光聚合物，磁性聚合物，放射性聚合物或导电聚合物可以形成检测和扩增的基础。 在另一个实施方案中，用荧光溶液，磁性溶液，放射性溶液或导电溶液溶胀的聚合物凝胶可以形成检测和扩增的基础。 在另一个实施方案中，足够的聚合物形式可通过目视检查来检测。

公开(公告)号：US20060251560A1

公开(公告)日：2006-11-09

申请号：US11402946

申请日：2006-04-13

申请人： Mario Costa ,  John Birks ,  Chunmin Pu ,  Kui Xu

发明人： Mario Costa ,  John Birks ,  Chunmin Pu ,  Kui Xu

IPC分类号： C01B25/16

CPC分类号： G01N1/4077 ,  Y10T436/25375

摘要： A method and system to consistently and automatically conditioning and delivering a solid-free liquid (filtrate) sample suitable for instrumental analysis is disclosed. A slurry, preferably a slurry produced by a sub-atmospheric pressure chlorate dioxide generating process, is fed through a filter to remove the solid phase and to provide the liquid phase on the downstream side of the filter, where the concentration of at least one dissolved component is determined.

摘要翻译： 公开了一种能够持续自动调节和输送适用于仪器分析的无固体液体（滤液）样品的方法和系统。 通过过滤器将浆料，优选由低于大气压的二氯甲烷生成过程产生的浆料进料，以除去固相并在过滤器的下游侧提供液相，其中至少一种溶解的浓度 组件确定。