-
1.
公开(公告)号:US5783568A
公开(公告)日:1998-07-21
申请号:US258307
申请日:1994-06-10
申请人: Joseph Schlessinger , Irit Lax , John E. Ladbury , Peng Cho Tang
发明人: Joseph Schlessinger , Irit Lax , John E. Ladbury , Peng Cho Tang
IPC分类号: A61K31/70 , A61K31/737 , A61K38/18 , C07K14/71 , A61K31/715 , C08B37/10
CPC分类号: A61K31/7024 , A61K31/70 , A61K31/7016 , A61K31/737 , A61K38/1825 , C07K14/71
摘要: The present invention relates to a method of treating in a mammal certain cancers, other cell proliferative diseases, and/or angiogenesis by using a salt or complex of a sulfated saccharide. The invention also relates to the use of mutant heparin binding growth factors that bind to the growth factor receptor, but not to heparin. The invention also provides pharmaceutical compositions for such methods.
摘要翻译: 本发明涉及通过使用硫酸化糖的盐或配合物在哺乳动物中治疗某些癌症,其它细胞增殖性疾病和/或血管发生的方法。 本发明还涉及结合生长因子受体而不是肝素的突变肝素结合生长因子的用途。 本发明还提供了用于这种方法的药物组合物。