公开(公告)号：US08852137B2

公开(公告)日：2014-10-07

申请号：US13336758

申请日：2011-12-23

申请人： Christopher Horvath ,  Ronald D. Bache ,  Laszlo O. Romoda ,  Guenther Grabner ,  Herbert A. Reitsamer ,  John R. Samples

发明人： Christopher Horvath ,  Ronald D. Bache ,  Laszlo O. Romoda ,  Guenther Grabner ,  Herbert A. Reitsamer ,  John R. Samples

IPC分类号： A61M5/00 ,  A61F9/007

CPC分类号： A61F9/00781 ,  A61F2210/0061

摘要： The invention generally relates to methods for implanting a soft gel shunt in the suprachoroidal space. In certain embodiments, methods of the invention involve inserting into the eye a hollow shaft configured to hold a soft gel intraocular shunt, deploying the soft gel shunt from the hollow shaft such that the shunt forms a passage from the anterior chamber of the eye to the suprachoroidal space of the eye, and withdrawing the hollow shaft from the eye.

摘要翻译： 本发明一般涉及在脉络膜上空间中植入软胶囊分流器的方法。 在某些实施方案中，本发明的方法涉及将眼睛插入眼睛中的中空轴，所述空心轴构造成保持软凝胶眼内分流，从中空轴展开软凝胶分流器，使得分流器形成从眼睛前房到 眼睛的脉络膜间隙，并从眼睛中取出空心轴。

公开(公告)号：US08758290B2

公开(公告)日：2014-06-24

申请号：US13336803

申请日：2011-12-23

申请人： Christopher Horvath ,  Ronald D. Bache ,  Laszlo O. Romoda ,  Guenther Grabner ,  Herbert A. Reitsamer ,  John R. Samples

发明人： Christopher Horvath ,  Ronald D. Bache ,  Laszlo O. Romoda ,  Guenther Grabner ,  Herbert A. Reitsamer ,  John R. Samples

IPC分类号： A61M5/00 ,  A61F11/00

CPC分类号： A61F9/00781

摘要： The invention generally relates to devices and methods for implanting a shunt in the suprachoroidal space of an eye. In certain aspects, devices of the invention include a housing, a deployment mechanism at least partially disposed within the housing, and a flexible hollow shaft coupled to the deployment mechanism, in which the shaft holds an intraocular shunt, and is configured to self-guide the shunt along a scleral spur of an eye as the shunt is deployed from the shaft. Such a device may be inserted into an eye and used to deploy a shunt within the eye such that a proximal portion of the shunt receives fluid from an anterior chamber of an eye and a distal portion of the shunt directs the fluid to the suprachoroidal space.

摘要翻译： 本发明一般涉及用于将分流器植入眼睛的脉络膜上空间的装置和方法。 在某些方面，本发明的装置包括壳体，至少部分地设置在壳体内的展开机构，以及联接到展开机构的柔性中空轴，其中轴保持眼内分流，并且构造成自导向 因为分流器从轴部署而沿着巩膜上的分支。 这种装置可被插入到眼睛中并且用于在眼睛内展开分路，使得分流器的近端部分接收来自眼睛的前房的流体并且分流器的远端部分将流体引导到脉管外空间。

公开(公告)号：US4654361A

公开(公告)日：1987-03-31

申请号：US822438

申请日：1986-01-27

申请人： John R. Samples ,  Alfred J. Lewy

发明人： John R. Samples ,  Alfred J. Lewy

IPC分类号： A61K31/40

CPC分类号： A61K31/40 ,  Y10S514/913

摘要： A method of lowering the intraocular pressure in a human having abnormally high intraocular pressure, comprisingadministering systemically thereto an amount of melatonin effective to lower the intraocular pressure.

摘要翻译： 一种降低眼内压异常的人眼内压的方法，其特征在于，全身给予一定量的有效降低眼内压的褪黑激素。

公开(公告)号：US20120165723A1

公开(公告)日：2012-06-28

申请号：US13336758

申请日：2011-12-23

申请人： Christopher Horvath ,  Ronald D. Bache ,  Laszlo O. Romoda ,  Guenther Grabner ,  Herbert A. Reitsamer ,  John R. Samples

发明人： Christopher Horvath ,  Ronald D. Bache ,  Laszlo O. Romoda ,  Guenther Grabner ,  Herbert A. Reitsamer ,  John R. Samples

IPC分类号： A61F9/007

CPC分类号： A61F9/00781 ,  A61F2210/0061

摘要： The invention generally relates to methods for implanting a soft gel shunt in the suprachoroidal space. In certain embodiments, methods of the invention involve inserting into the eye a hollow shaft configured to hold a soft gel intraocular shunt, deploying the soft gel shunt from the hollow shaft such that the shunt forms a passage from the anterior chamber of the eye to the suprachoroidal space of the eye, and withdrawing the hollow shaft from the eye.

摘要翻译： 本发明一般涉及在脉络膜上空间中植入软胶囊分流器的方法。 在某些实施方案中，本发明的方法涉及将眼睛插入眼睛中的中空轴，所述空心轴构造成保持软凝胶眼内分流，从中空轴展开软凝胶分流器，使得分流器形成从眼睛前房到 眼睛的脉络膜间隙，并从眼睛中取出空心轴。

公开(公告)号：US20120165722A1

公开(公告)日：2012-06-28

申请号：US13336803

申请日：2011-12-23

申请人： Christopher Horvath ,  Ronald D. Bache ,  Laszlo O. Romoda ,  Guenther Grabner ,  Herbert A. Reitsamer ,  John R. Samples

发明人： Christopher Horvath ,  Ronald D. Bache ,  Laszlo O. Romoda ,  Guenther Grabner ,  Herbert A. Reitsamer ,  John R. Samples

IPC分类号： A61F9/007

CPC分类号： A61F9/00781

摘要： The invention generally relates to devices and methods for implanting a shunt in the suprachoroidal space of an eye. In certain aspects, devices of the invention include a housing, a deployment mechanism at least partially disposed within the housing, and a flexible hollow shaft coupled to the deployment mechanism, in which the shaft holds an intraocular shunt, and is configured to self-guide the shunt along a scleral spur of an eye as the shunt is deployed from the shaft. Such a device may be inserted into an eye and used to deploy a shunt within the eye such that a proximal portion of the shunt receives fluid from an anterior chamber of an eye and a distal portion of the shunt directs the fluid to the suprachoroidal space.

摘要翻译： 本发明一般涉及用于将分流器植入眼睛的脉络膜上空间的装置和方法。 在某些方面，本发明的装置包括壳体，至少部分地设置在壳体内的展开机构，以及联接到展开机构的柔性中空轴，其中轴保持眼内分流，并且构造成自导向 因为分流器从轴部署而沿着巩膜上的分支。 这种装置可被插入到眼睛中并且用于在眼睛内展开分路，使得分流器的近端部分接收来自眼睛的前房的流体并且分流器的远端部分将流体引导到脉管外空间。