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公开(公告)号:US20060147490A1
公开(公告)日:2006-07-06
申请号:US10526965
申请日:2003-09-05
申请人: Tim Bowden , Fredrik Nederberg , Jon Hillborn
发明人: Tim Bowden , Fredrik Nederberg , Jon Hillborn
CPC分类号: C08G83/003 , A61K9/0024 , A61K9/1075 , A61K9/2853 , A61K9/5146 , C08G63/6852 , C08G63/6922 , C08G63/912 , C09D201/005
摘要: The present invention provides a biodegradable, biocompatible polymer that is capable of forming particles (micelles), vesicles, surfaces and membranes, and other structures in which a biologically active agent, e.g. a drug, can be incorporated in such a way that its release to the host can be controlled to a high degree of accuracy, or in where surfaces of the formed polymers can be used to increase the hemeo compatibility of biomaterials. The present invention provides polymer compounds comprising at least one biodegradable polyester having a terminal functional group based on hydrophilic moieties from a phospholipid.
摘要翻译: 本发明提供了一种可生物降解的生物相容性聚合物,其能够形成颗粒(胶束),囊泡,表面和膜以及其它结构,其中生物活性剂例如 药物可以以能够高度准确地控制其释放到宿主的方式,或者可以使用形成的聚合物的表面来增加生物材料的血液相容性的方式来引入。 本发明提供包含至少一种具有基于磷脂亲水部分的末端官能团的可生物降解聚酯的聚合物化合物。