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1.1-Alkyl-3-thio-substituted indole-2-alkynoic acids useful for the treatment of alzheimer's disease and related conditions 审中-公开
标题翻译: 可用于治疗阿尔茨海默病和相关病症的1-烷基-3-硫代取代的吲哚-2-炔酸公开(公告)号:US20070142453A1
公开(公告)日:2007-06-21
申请号:US10580286
申请日:2004-11-25
申请人: Dirk Beher , Michela Bettari , Ian Churcher , Benito Munoz , Petpiboon Prasit , Abdul Quddus , Nicholas Stock , Jonathan Wrigley
发明人: Dirk Beher , Michela Bettari , Ian Churcher , Benito Munoz , Petpiboon Prasit , Abdul Quddus , Nicholas Stock , Jonathan Wrigley
IPC分类号: A61K31/404 , C07D209/36
CPC分类号: C07D417/12 , A61K31/405 , C07D209/30 , C07D209/36 , C07D403/12
摘要: Compounds of formula I: modulate the activity of γ-secretase, and hence find use in treatment or prevention of Alzheimer's disease and related conditions.
摘要翻译: 式I化合物:调节γ-分泌酶的活性,因此可用于治疗或预防阿尔茨海默病和相关病症。