公开(公告)号：US09056164B2

公开(公告)日：2015-06-16

申请号：US11981429

申请日：2007-10-31

申请人： Leon J. Tate ,  James H. Shigeno ,  Jared E. Neff ,  Scott R. Griffith ,  Joseph E. Bisegna ,  Paul J. Miller ,  Scott Yanke

发明人： Leon J. Tate ,  James H. Shigeno ,  Jared E. Neff ,  Scott R. Griffith ,  Joseph E. Bisegna ,  Paul J. Miller ,  Scott Yanke

IPC分类号： A61M5/00 ,  A61M25/00 ,  A61M5/172 ,  G06F19/00

CPC分类号： A61M5/172 ,  A61K51/00 ,  A61M5/007 ,  A61M5/14 ,  A61M5/16822 ,  A61M5/3146 ,  A61M2005/1402 ,  G06F19/3468 ,  G16H20/17

摘要： A fluid path set for a fluid delivery system includes a tube coil that is designed to optimally position one or more volumes of a pharmaceutical within an ionization chamber to measure and prepare a pharmaceutical dose for administration to a patient. The fluid path set includes a medical fluid component having a first tubing section for connection to a source of a medical fluid, a pharmaceutical component having a second tubing section for connection to a source of a pharmaceutical, and a coil assembly which includes the tube coil. The tube coil may be maintained in a desired dimensional geometry by means of a core structure around which the tube coil is positioned.

摘要翻译： 设置用于流体输送系统的流体路径包括管线圈，其设计成在离子化室内最佳地定位药物的一个或多个体积以测量并制备用于给予患者的药物剂量。 流体路径组包括具有用于连接到医用流体源的第一管道部分的药物流体部件，具有用于连接到药物源的第二管道部分的药物部件和包括管线圈的线圈组件 。 管线圈可以通过围绕管线圈定位的芯结构保持在期望的尺寸几何形状。

公开(公告)号：US20150105736A1

公开(公告)日：2015-04-16

申请号：US14576354

申请日：2014-12-19

申请人： Joseph E. Bisegna ,  Jared E. Neff

发明人： Joseph E. Bisegna ,  Jared E. Neff

IPC分类号： A61M5/315

CPC分类号： A61M5/31513

摘要： A plunger cover for use with a syringe includes a sealing portion adapted to form a seal with the syringe and a central portion adapted to contact fluid within the syringe. The central portion can, for example, be more rigid than the sealing portion. The sealing portion and the central portion are connected in an overmolding process. The sealing portion can, for example, be formed from a thermoplastic elastomer or a thermoplastic polyurethane. The central portion can, for example, be formed from polypropylene, acrylonitrile butadiene styrene, polycarbonate or copolymers thereof.

摘要翻译： 与注射器一起使用的柱塞盖包括适于与注射器形成密封的密封部分和适于接触注射器内的流体的中心部分。 中心部分可以例如比密封部分更刚性。 密封部分和中心部分在二次模制过程中连接。 密封部分可以例如由热塑性弹性体或热塑性聚氨酯形成。 中心部分可以例如由聚丙烯，丙烯腈丁二烯苯乙烯，聚碳酸酯或其共聚物形成。

公开(公告)号：US08926569B2

公开(公告)日：2015-01-06

申请号：US11686000

申请日：2007-03-14

申请人： Joseph E. Bisegna ,  Jared Neff

发明人： Joseph E. Bisegna ,  Jared Neff

IPC分类号： A61M5/315

CPC分类号： A61M5/31513

摘要： A plunger cover for use with a syringe includes a sealing portion adapted to form a seal with the syringe and a central portion adapted to contact fluid within the syringe. The central portion can, for example, be more rigid than the sealing portion. The sealing portion and the central portion are connected in an overmolding process. The sealing portion can, for example, be formed from a thermoplastic elastomer or a thermoplastic polyurethane. The central portion can, for example, be formed from polypropylene, acrylonitrile butadiene styrene, polycarbonate or copolymers thereof.

摘要翻译： 与注射器一起使用的柱塞盖包括适于与注射器形成密封的密封部分和适于接触注射器内的流体的中心部分。 中心部分可以例如比密封部分更刚性。 密封部分和中心部分在二次模制过程中连接。 密封部分可以例如由热塑性弹性体或热塑性聚氨酯形成。 中心部分可以例如由聚丙烯，丙烯腈丁二烯苯乙烯，聚碳酸酯或其共聚物形成。

公开(公告)号：US20080177126A1

公开(公告)日：2008-07-24

申请号：US11981429

申请日：2007-10-31

申请人： Leon J. Tate ,  James H. Shigeno ,  Steven C. Rygg ,  Jared E. Neff ,  Scott R. Griffith ,  Joseph E. Bisegna ,  Edward Ilgenfritz ,  Paul J. Miller ,  Scott Yanke

发明人： Leon J. Tate ,  James H. Shigeno ,  Steven C. Rygg ,  Jared E. Neff ,  Scott R. Griffith ,  Joseph E. Bisegna ,  Edward Ilgenfritz ,  Paul J. Miller ,  Scott Yanke

IPC分类号： A61M36/08

CPC分类号： A61M5/172 ,  A61K51/00 ,  A61M5/007 ,  A61M5/14 ,  A61M5/16822 ,  A61M5/3146 ,  A61M2005/1402 ,  G06F19/3468 ,  G16H20/17

摘要： A fluid path set for a fluid delivery system includes a tube coil that is designed to optimally position one or more volumes of a pharmaceutical within an ionization chamber to optimally measure and prepare a pharmaceutical dose for administration to a patient. The tube coil may be maintained in a desired dimensional geometry by means of a core structure around which the tube coil is positioned. Novel developments in radiopharmaceutical administration methods and systems include, but are not limited to, the configuration and layout of a fluid path set for use in a fluid delivery system, arrangements for piercing and drawing fluid from a pharmaceutical container (such as a vial), arrangements for optimizing the positioning of a tube coil within an ionization chamber, a handling system for transporting vial shields that maintain an operator's hand and fingers at a safe distance from a pharmaceutical vial, a method for calibrating a radiopharmaceutical delivery system in which the difference between the expected and measured activities of two radioisotopes are used to calculate an estimated error in the measured activity of a third radioisotope and a vial access system that ensures an optimal draw of fluid from a radiopharmaceutical container.

摘要翻译： 设置用于流体输送系统的流体路径包括管线圈，其设计成在电离室内优化地定位药物的一个或多个体积，以最佳地测量并制备用于给予患者的药物剂量。 管线圈可以通过围绕管线圈定位的芯结构保持在期望的尺寸几何形状。 放射性药物管理方法和系统的新发展包括但不限于用于流体输送系统的流体路径组的配置和布局，用于从药物容器（例如小瓶）刺穿和抽取流体的布置， 用于优化电离室内的管线圈的定位的布置，用于运输维护操作者的手和手指与药物瓶的安全距离的小瓶护罩的处理系统，用于校准放射性药物递送系统的方法，其中， 使用两个放射性同位素的预期和测量的活动来计算第三放射性同位素和小瓶进入系统的测量活动的估计误差，其确保从放射性药物容器中最佳地吸取流体。

公开(公告)号：US20070219508A1

公开(公告)日：2007-09-20

申请号：US11686000

申请日：2007-03-14

申请人： Joseph E. Bisegna ,  Jared Neff

发明人： Joseph E. Bisegna ,  Jared Neff

IPC分类号： A61M5/315

CPC分类号： A61M5/31513

摘要： A plunger cover for use with a syringe includes a sealing portion adapted to form a seal with the syringe and a central portion adapted to contact fluid within the syringe. The central portion can, for example, be more rigid than the sealing portion. The sealing portion and the central portion are connected in an overmolding process. The sealing portion can, for example, be formed from a thermoplastic elastomer or a thermoplastic polyurethane. The central portion can, for example, be formed from polypropylene, acrylonitrile butadiene styrene, polycarbonate or copolymers thereof.

摘要翻译： 与注射器一起使用的柱塞盖包括适于与注射器形成密封的密封部分和适于接触注射器内的流体的中心部分。 中心部分可以例如比密封部分更刚性。 密封部分和中心部分在二次模制过程中连接。 密封部分可以例如由热塑性弹性体或热塑性聚氨酯形成。 中心部分可以例如由聚丙烯，丙烯腈丁二烯苯乙烯，聚碳酸酯或其共聚物形成。