公开(公告)号：US20070048390A1

公开(公告)日：2007-03-01

申请号：US11347509

申请日：2006-02-02

申请人： Nigel Atherton ,  Michael Gaitonde ,  Joseph Totten ,  Peter Davies ,  Raymond Pratt

发明人： Nigel Atherton ,  Michael Gaitonde ,  Joseph Totten ,  Peter Davies ,  Raymond Pratt

IPC分类号： A61K33/24 ,  A61K31/59

CPC分类号： A61K33/24 ,  Y10S424/06 ,  Y10S514/825 ,  Y10S514/836 ,  Y10S514/90

摘要： The invention provides a method for enhancing bone formation, inhibiting osteoclastic differentiation and/or activating osteoblastic differentiation whereby to manage, treat or achieve prophylaxis of bone disease which comprises administering to a human or animal subject suffering from, or susceptible to bone disease a therapeutically or prophylactically effective amount of a lanthanum compound and a bone enhancing agent, such as vitamin D.

摘要翻译： 本发明提供了一种增强骨形成，抑制破骨细胞分化和/或激活成骨细胞分化的方法，其用于管理，治疗或实现骨疾病的预防，其包括向患有或易于骨疾病的人或动物受试者施用治疗或 预防有效量的镧化合物和骨增强剂，如维生素D.

公开(公告)号：US20210096825A1

公开(公告)日：2021-04-01

申请号：US16879377

申请日：2020-05-20

申请人： Kristopher Scott Gray ,  Nicolas Raymond Kruk ,  Nathan David McWilliams ,  Nathan Joseph Totten ,  Mindaugas Andrius Idzelis

发明人： Kristopher Scott Gray ,  Nicolas Raymond Kruk ,  Nathan David McWilliams ,  Nathan Joseph Totten ,  Mindaugas Andrius Idzelis

IPC分类号： G06F8/30 ,  H04L29/06 ,  H04L29/08

摘要： Resolving a dynamic request from a local web component rendered on a development server executing on a user client device. A cache is located in the user client device and is accessible to the development server. The development server receives a first request for information from the local web component via a web browser, intercepts the first request at a proxy override module and transmits the first request to a cloud computing service provider's server. The development server receives a response from the cloud computing service provider's server in reply to the first request, transmits the response from the development server to the local web component, stores in the cache the response received at the development server from the cloud computing service provider's server in reply to the first request for information. The development server receives a subsequent request for the information from the local web component via the web browser, accesses the response to the subsequent request from the cache, and transmits the response accessed from the cache to the local web component.