公开(公告)号：US07048941B2

公开(公告)日：2006-05-23

申请号：US10107664

申请日：2002-03-26

申请人： Paul Altaffer ,  Alexander R. Conn ,  Joshua A. Duberman ,  David Lytle ,  Kerry Hughes

发明人： Paul Altaffer ,  Alexander R. Conn ,  Joshua A. Duberman ,  David Lytle ,  Kerry Hughes

IPC分类号： A61K47/00 ,  A61K35/78

CPC分类号： A23G1/48 ,  A23G1/325 ,  A23G1/426 ,  A23G3/34 ,  A23L33/10 ,  A23L33/105 ,  A23L33/175 ,  A23L33/30 ,  A61K9/0056

摘要： A novel chocolate product for use in delivering medicaments and/or nutrients to animals, particularly humans, specially formulated so that the craving for such product by animals, particularly humans, is significantly greater than the craving for chocolate conventionally used in pharmaceutical compositions and the concentration, optimization, and the addition of endogenous and exogenous ingredients to increase such craving as well as to treat specific indications. The chocolate product contains: from about 0.5 to about 200 milligrams, more preferably from about 5 to about 20 milligrams, of one or more biogenic amines per 1 gram of the chocolate product; from about 10 to about 500 milligrams, more preferably form about 20 to about 200 milligrams, of one or more amino acids per 1 gram of the chocolate product; (C) from about 1 microgram to about 20 milligrams, more preferably from about 10 micrograms to about 10 milligrams, of one or more of: methyl tetrahydroisoquinoline, N-acylethanolamines, and/or anandamide and/or salsolinol per 1 gram of the chocolate product; (D) from about 0.2 to about 30 milligrams of at least one trace mineral per 1 gram of the chocolate product; and (E) from 0.6 to about 500 milligrams, more preferably from about 35 to about 100 milligrams, of one or more methylxanthine alkaloids per 1 gram of the chocolate product. The chocolate product used in this invention also preferably contains effective amounts of at least one chocolate aroma and at least one vanilla aroma.

摘要翻译： 用于向动物，特别是人类递送药物和/或营养物质的新颖的巧克力产品，特别配制成使得动物，特别是人类对这种产品的渴望明显大于药物组合物中常规使用的巧克力的渴望，并且浓度 ，优化和添加内源和外源成分以增加这种渴望以及治疗特定适应症。 所述巧克力产品包含：每1克巧克力产品约0.5至约200毫克，更优选约5至约20毫克的一种或多种生物胺; 约10至约500毫克，更优选形成约20至约200毫克的每1g巧克力产品中的一种或多种氨基酸; （C）每1g巧克力约1微克至约20毫克，更优选约10微克至约10毫克的一种或多种以下的一种或多种：甲基四氢异喹啉，N-酰基乙醇胺和/或一种和酰胺和/或沙林多酚 产品; （D）每1克巧克力产品约0.2至约30毫克的至少一种痕量矿物; 和（E）每1克巧克力产品0.6至约500毫克，更优选约35至约100毫克的一种或多种甲基黄嘌呤生物碱。 用于本发明的巧克力产品还优选含有有效量的至少一种巧克力香气和至少一种香草香气。

公开(公告)号：US4172705A

公开(公告)日：1979-10-30

申请号：US895686

申请日：1978-04-12

申请人： James M. Castro ,  Joshua A. Duberman ,  Robert T. Moore

发明人： James M. Castro ,  Joshua A. Duberman ,  Robert T. Moore

IPC分类号： G01N27/42 ,  G01N31/00 ,  G01N31/12

CPC分类号： G01N31/005 ,  G01N27/423 ,  Y10T436/18

摘要： Process and apparatus for micro-coulometric determination of sulfur in hydrocarbon samples in which interference of chlorine and oxides of nitrogen is minimized. The process comprises the steps of oxidizing the sample, scrubbing the oxidized sample with a tin-containing agent and coulometrically titrating the sample thereafter.

摘要翻译： 用于微量库仑测定烃样品中的硫的方法和装置，其中氯和氮的氧化物的干扰最小化。 该方法包括氧化样品，用含锡试剂洗涤氧化样品并随后对其进行库仑滴定的步骤。