公开(公告)号：US07250270B2

公开(公告)日：2007-07-31

申请号：US10462091

申请日：2003-06-13

申请人： Marianna Goldrick ,  Juanita C. Gonzales

发明人： Marianna Goldrick ,  Juanita C. Gonzales

IPC分类号： G01N1/30 ,  G01N33/48

CPC分类号： G01N1/30

摘要： The present invention concerns the methods and compositions for preparing a tissue section or biological sample, particularly to preserve RNA in the section or sample, by not exposing or contacting the sample or section to a solution that is composed of mostly water. Tissue sections can be fixed, stained, and dehydrated for subsequent manipulation, including laser capture microdissection (LCM) for further analysis using methods and/or compositions of the invention.

摘要翻译： 本发明涉及用于制备组织切片或生物样品的方法和组合物，特别是通过不将样品或部分暴露或接触到由大多数水组成的溶液而将部分或样品中的RNA保留。 组织切片可以固定，染色和脱水以用于随后的操作，包括使用本发明的方法和/或组合物进一步分析的激光捕获显微切割（LCM）。