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公开(公告)号:US20130150565A1
公开(公告)日:2013-06-13
申请号:US13160091
申请日:2011-06-14
IPC分类号: C07K14/47
CPC分类号: C07K14/4726 , A01K2217/05 , C07K14/785
摘要: Provided are isolated collectin (CL-L2s) genes including a base sequence set out in SEQ ID NO: 1, 3, 5, 7, 9, 12, 36, 38 or 40 relating to a novel collectin which are expected to exhibit an antibacterial activity, an antiviral activity and the like particularly in a human body; and isolated collectin proteins including an amino acid sequence set out in SEQ ID NO: 2, 4, 6, 8, 10, 13, 37, 39 or 41 and derivatives and fragments thereof.
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公开(公告)号:US20090275740A1
公开(公告)日:2009-11-05
申请号:US12334052
申请日:2008-12-12
IPC分类号: C07K14/42
CPC分类号: C07K14/4726 , A01K2217/05 , C07K14/785
摘要: Provided are isolated collectin (CL-L2s) genes including a base sequence set out in SEQ ID NO: 1, 3, 5, 7, 9, 12, 36, 38 or 40 relating to a novel collectin which are expected to exhibit an antibacterial activity, an antiviral activity and the like particularly in a human body; and isolated collectin proteins including an amino acid sequence set out in SEQ ID NO: 2, 4, 6, 8, 10, 13, 37, 39 or 41 and derivatives and fragments thereof.
摘要翻译: 提供了分离的集合蛋白(CL-L2)基因,其包括与预期显示抗细菌剂的新型聚集蛋白相关的SEQ ID NO:1,3,5,7,9,12,32,38或40所示的碱基序列 活动,抗病毒活性等,特别是在人体内; 和分离的集合蛋白,包括SEQ ID NO:2,4,6,8,10,13,37,39或41所示的氨基酸序列及其衍生物和片段。
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公开(公告)号:US20090048165A1
公开(公告)日:2009-02-19
申请号:US12169502
申请日:2008-07-08
CPC分类号: A61K38/1709
摘要: Disclosed are anti-HIV agents which comprise a mannose binding protein (MBP) as an active component and are useful for effectively inhibiting progress of diseases state in and useful in therapy for individuals infected with human immunodeficiency virus (HIV). Also disclosed are a method for evaluating an anti-HIV activity of MBP comprising the step of culturing HIV infected cells under the presence of MBP.
摘要翻译: 公开了包含作为活性成分的甘露糖结合蛋白(MBP)的抗HIV剂,并且可有效地有效地抑制感染人类免疫缺陷病毒(HIV)的个体的疾病状态并用于治疗。 还公开了评估MBP的抗HIV活性的方法,包括在MBP存在下培养HIV感染细胞的步骤。
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公开(公告)号:US08604162B2
公开(公告)日:2013-12-10
申请号:US13160091
申请日:2011-06-14
IPC分类号: C07K14/00
CPC分类号: C07K14/4726 , A01K2217/05 , C07K14/785
摘要: Provided are isolated collectin (CL-L2s) genes including a base sequence set out in SEQ ID NO: 1, 3, 5, 7, 9, 12, 36, 38 or 40 relating to a novel collectin which are expected to exhibit an antibacterial activity, an antiviral activity and the like particularly in a human body; and isolated collectin proteins including an amino acid sequence set out in SEQ ID NO: 2, 4, 6, 8, 10, 13, 37, 39 or 41 and derivatives and fragments thereof.
摘要翻译: 提供了分离的集合蛋白(CL-L2)基因,其包括与预期显示抗细菌剂的新型聚集蛋白相关的SEQ ID NO:1,3,5,7,9,12,32,38或40所示的碱基序列 活动,抗病毒活性等,特别是在人体内; 和分离的集合蛋白,包括SEQ ID NO:2,4,6,8,10,13,37,39或41所示的氨基酸序列及其衍生物和片段。
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公开(公告)号:US20070191265A1
公开(公告)日:2007-08-16
申请号:US11691914
申请日:2007-03-27
CPC分类号: A61K38/1709
摘要: Disclosed are anti-HIV agents which comprise a mannose binding protein (MBP) as an active component and are useful for effectively inhibiting progress of diseases state in and useful in therapy for individuals infected with human immunodeficiency virus (HIV). Also disclosed are a method for evaluating an anti-HIV activity of MBP comprising the step of culturing HIV infected cells under the presence of MBP.
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公开(公告)号:US20070190652A1
公开(公告)日:2007-08-16
申请号:US11691946
申请日:2007-03-27
CPC分类号: A61K38/1709
摘要: Disclosed are anti-HIV agents which comprise a mannose binding protein (MBP) as an active component and are useful for effectively inhibiting progress of diseases state in and useful in therapy for individuals infected with human immunodeficiency virus (HIV). Also disclosed are a method for evaluating an anti-HIV activity of MBP comprising the step of culturing HIV infected cells under the presence of MBP.
摘要翻译: 公开了包含作为活性成分的甘露糖结合蛋白(MBP)的抗HIV剂,并且可有效地有效地抑制感染人类免疫缺陷病毒(HIV)的个体的疾病状态并用于治疗。 还公开了评估MBP的抗HIV活性的方法,包括在MBP存在下培养HIV感染细胞的步骤。
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公开(公告)号:US20070184477A1
公开(公告)日:2007-08-09
申请号:US11691921
申请日:2007-03-27
CPC分类号: A61K38/1709
摘要: Disclosed are anti-HIV agents which comprise a mannose binding protein (MBP) as an active component and are useful for effectively inhibiting progress of diseases state in and useful in therapy for individuals infected with human immunodeficiency virus (HIV). Also disclosed are a method for evaluating an anti-HIV activity of MBP comprising the step of culturing HIV infected cells under the presence of MBP.
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公开(公告)号:US20050123899A1
公开(公告)日:2005-06-09
申请号:US10500774
申请日:2003-06-30
CPC分类号: A61K38/1709
摘要: Disclosed are anti-HIV agents which comprise a mannose binding protein (MBP) as an active component and are useful for effectively inhibiting progress of diseases state in and useful in therapy for individuals infected with human immunodeficiency virus (HIV). Also disclosed are a method for evaluating an anti-HIV activity of MBP comprising the step of culturing HIV infected cells under the presence of MBP.
摘要翻译: 公开了包含作为活性成分的甘露糖结合蛋白(MBP)的抗HIV剂,并且可有效地有效地抑制感染人类免疫缺陷病毒(HIV)的个体的疾病状态并用于治疗。 还公开了评估MBP的抗HIV活性的方法,包括在MBP存在下培养HIV感染细胞的步骤。
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公开(公告)号:US07985833B2
公开(公告)日:2011-07-26
申请号:US12334052
申请日:2008-12-12
CPC分类号: C07K14/4726 , A01K2217/05 , C07K14/785
摘要: Provided are isolated collectin (CL-L2s) genes including a base sequence set out in SEQ ID NO: 1, 3, 5, 7, 9, 12, 36, 38 or 40 relating to a novel collectin which are expected to exhibit an antibacterial activity, an antiviral activity and the like particularly in a human body; and isolated collectin proteins including an amino acid sequence set out in SEQ ID NO: 2, 4, 6, 8, 10, 13, 37, 39 or 41 and derivatives and fragments thereof.
摘要翻译: 提供了分离的集合蛋白(CL-L2)基因,其包括与预期显示抗细菌剂的新型聚集蛋白相关的SEQ ID NO:1,3,5,7,9,12,32,38或40所示的碱基序列 活动,抗病毒活性等,特别是在人体内; 和分离的集合蛋白,包括SEQ ID NO:2,4,6,8,10,13,37,39或41所示的氨基酸序列及其衍生物和片段。
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