公开(公告)号：US20210370285A1

公开(公告)日：2021-12-02

申请号：US16889676

申请日：2020-06-01

申请人： Keith Wetherby ,  Xinjing Wang ,  Maria Apostolopoulou

发明人： Keith Wetherby ,  Xinjing Wang ,  Maria Apostolopoulou

IPC分类号： B01L3/00

摘要： An apparatus and method for collecting multi-tiered particles from various biological samples for use in downstream biological procedures. Two filters compatible with the device, and of different pore size, are connected via a conduit or are integrated into the conduit. A biological sample is driven through the conduit by applying pressure to one of the inlet ports. The flow of the biological sample is directed to the desired output port by positioning of the internal switch. A switch directs the fluid to flow within the device to elute trapped particles captured on the filters. The apparatus allows for the collection of unstimulated, intact particles without the need for multiple redraws of sample or filtrate. Collection and analysis of biological samples are valuable for correct diagnosis and therapy of a wide variety of different conditions.