公开(公告)号：US06586620B1

公开(公告)日：2003-07-01

申请号：US10140795

申请日：2002-05-06

申请人： Khushrav Crawford ,  Valentin Rautenstrauch ,  Arnoldus Uijttewaal

发明人： Khushrav Crawford ,  Valentin Rautenstrauch ,  Arnoldus Uijttewaal

IPC分类号： C07C6974

CPC分类号： C07D307/93 ,  C07C67/327 ,  C07C2601/10 ,  C07D303/48 ,  C07C69/738

摘要： The present invention discloses a process for the preparation of a compound according to formula wherein R1 is a C3-C7 alkyl group and R2 is a C1 to C4, linear or branched, alkyl radical, more preferably a methyl group, characterized in that the process includes the isomerisation of an epoxide of formula wherein R1 and R2 have the meaning given in formula (I), in the presence of an acidic isomerisation agent, a thermal treatment or a combination thereof. The process according to the invention allows the preparation of the cyclopentenyl compounds of formula (I) on an industrial scale. The compounds are important starting products for the production of appreciated perfuming ingredients in particular methyl dihydrojasmonates.

摘要翻译： 本发明公开了一种制备化合物的方法，其中R 1为C 3 -C 7烷基，R 2为C 1至C 4直链或支链烷基，更优选甲基，其特征在于该方法包括 在酸性异构化试剂，热处理或其组合的存在下，式（I）中给出的甲酰脲的环氧化物的异构化具有式（I）中给出的含义。 根据本发明的方法允许以工业规模制备式（I）的环戊烯基化合物。 这些化合物是用于生产特别是二氢茉芬酸甲酯的感觉加香成分的重要起始产物。