公开(公告)号：US10413621B2

公开(公告)日：2019-09-17

申请号：US13502852

申请日：2010-10-19

申请人： James Basilion ,  Kirti Dhingra ,  Thomas J. Meade ,  Sarah Grace Kamper

发明人： James Basilion ,  Kirti Dhingra ,  Thomas J. Meade ,  Sarah Grace Kamper

IPC分类号： A61B5/055 ,  A61K49/08 ,  G01N33/569

摘要： A composition for imaging a cell includes a first imaging probe and a second imaging probe that include respectively a first reporter moiety and a second reporter moiety. The first reporter moiety and the second reporter moiety form a signaling complex that produces a detectable signal when the first imaging probe and second imaging probe complex with first and second biomarkers of the cell.

公开(公告)号：US20120207684A1

公开(公告)日：2012-08-16

申请号：US13502852

申请日：2010-10-19

申请人： James Basilion ,  Kirti Dhingra ,  Thomas J. Meade ,  Sarah Grace Kamper

发明人： James Basilion ,  Kirti Dhingra ,  Thomas J. Meade ,  Sarah Grace Kamper

IPC分类号： A61K49/10 ,  G01N24/08

摘要： A composition for imaging a cell includes a first imaging probe and a second imaging probe that include respectively a first reporter moiety and a second reporter moiety. The first reporter moiety and the second reporter moiety form a signaling complex that produces a detectable signal when the first imaging probe and second imaging probe complex with first and second biomarkers of the cell.

摘要翻译： 用于对细胞成像的组合物包括第一成像探针和第二成像探针，其分别包括第一报道部分和第二报道部分。 当第一成像探针和第二成像探针与细胞的第一和第二生物标志物复合时，第一报道部分和第二报道部分形成信号复合物，产生可检测信号。