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1.发明授权Process for manufacture of cephalosporin such as ceftazidime and intermediate thereof 失效头孢菌素如头孢他啶及其中间体的制造方法
公开(公告)号：US5831085A
公开(公告)日：1998-11-03
申请号：US845735
申请日：1997-04-25
Applicant: Debashish Datta , Bishwa Prakash Rai , Kishor Mehre
Inventor： Debashish Datta , Bishwa Prakash Rai , Kishor Mehre
IPC: C07D277/20 , C07D501/00 , C07D501/46 , C07D277/587
CPC classification number: C07D277/587 , C07D501/00
Abstract: This invention relates to reactive derivative of 2-(2-amino-4-thiazolyl)-(Z)-2-�(1-tert butoxycarbonyl-l-methylethoxy) imino!acetic acid of the following formula I ##STR1## as well as to the use thereof in the manufacture of cephalosporin antibiotic such as ceftazidime of formula II. ##STR2##
Abstract translation: 本发明涉及下式I的2-（2-氨基-4-噻唑基） - （Z）-2 - [（1-叔丁氧基羰基-1-甲基乙氧基）亚氨基]乙酸的活性衍生物， 以及其在制备头孢菌素抗生素如式II头孢他啶的用途。
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