Dialysis preparation
    1.
    发明申请
    Dialysis preparation 审中-公开
    透析准备

    公开(公告)号:US20090294360A1

    公开(公告)日:2009-12-03

    申请号:US11794824

    申请日:2006-01-06

    IPC分类号: B01D61/32 A61K47/02

    摘要: The present invention provides a pharmaceutical composition for dialysis wherein the decline of ionized calcium concentration in an acetate-free bicarbonate dialysate comprising no acetic acid and/or sodium acetate is controlled. The present invention further provides a dialysis agent A that comprises electrolytes, citric acid and/or citrate as pH adjuster, and/or glucose, for preparation of bicarbonate dialysates; the agent A characterized by being adjusted by citric acid and/or citrate so as to keep the electrolyte ionized calcium concentration not less than 1 mmol/L in a prepared bicarbonate dialysate. In a specific aspect of the present invention, sodium citrate is used as citrate, and the present invention provides a dialysate obtained from above.

    摘要翻译: 本发明提供一种用于透析的药物组合物,其中控制不含乙酸和/或乙酸钠的不含乙酸酯的碳酸氢盐透析液中电离钙浓度的下降。 本发明还提供一种透析剂A,其包含用于制备碳酸氢盐透析液的电解质,柠檬酸和/或柠檬酸盐作为pH调节剂和/或葡萄糖; 该试剂A的特征在于用柠檬酸和/或柠檬酸盐调节,以使电解质在制备的碳酸氢盐透析液中电离钙离子浓度不小于1mmol / L。 在本发明的具体方面,柠檬酸钠用作柠檬酸盐,本发明提供由上述获得的透析液。