公开(公告)号：US4612302A

公开(公告)日：1986-09-16

申请号：US550978

申请日：1983-11-14

申请人： Sandor Szabo ,  Klaus W. Usadel ,  Horst Kessler

发明人： Sandor Szabo ,  Klaus W. Usadel ,  Horst Kessler

IPC分类号： A61K38/00 ,  A61K38/31 ,  C07K14/655 ,  A61K37/24 ,  C07K7/26

CPC分类号： C07K14/6555 ,  A61K38/31 ,  Y10S514/806 ,  Y10S930/16 ,  Y10S930/26

摘要： A method of increasing the clearance of particles from the blood stream of a vertebrate, which comprises administering to a vertebrate having a surplus of particles in the blood stream of the vertebrate an amount of a somatostatin analogue sufficient to increase phagocytosis in the vertebrate is disclosed along with a method treating vascular lesions or deterioration of biological membranes comprising the step of administering to a human or other mammal suspected of having one or more vascular lesions or of having deterioration of a biological membrane in the liver of said human or mammal an amount of a somatostatin analogue sufficient to reduce the number or severity of said lesions or to prevent further deterioration or reduce the extent of deterioration of said membrane.

摘要翻译： 一种从脊椎动物的血流中增加颗粒间隙的方法，其包括向脊椎动物的血流中具有多余颗粒的脊椎动物施用足以增加脊椎动物吞噬作用的生长抑素类似物的量 包括处理血管病变或生物膜恶化的方法，包括向疑似患有一种或多种血管病变的人或其他哺乳动物施用或在所述人或哺乳动物的肝脏中使生物膜变质的步骤 生长抑素类似物足以减少所述病变的数量或严重程度，或防止进一步恶化或降低所述膜的恶化程度。