公开(公告)号：US20050095618A1

公开(公告)日：2005-05-05

申请号：US10901744

申请日：2004-07-28

申请人： Kwok Tsui ,  Kwok Fung ,  Mary Miu Waye ,  Yuk Ming Lo ,  Siu Chung Chim ,  Wai Kwun Chiu ,  Siu Lun Tam ,  Kay Sheung Chan

发明人： Kwok Tsui ,  Kwok Fung ,  Mary Miu Waye ,  Yuk Ming Lo ,  Siu Chung Chim ,  Wai Kwun Chiu ,  Siu Lun Tam ,  Kay Sheung Chan

IPC分类号： A61K39/00 ,  C07K14/165 ,  C12Q1/68 ,  A61K48/00 ,  C07H21/02 ,  C07H21/04 ,  C07K14/00

CPC分类号： C07K14/005 ,  A61K39/00 ,  A61K2039/53 ,  C12N2770/20022

摘要： The present invention relates to the fields of immunochemistry and pharmacology. Methods and compositions are described for the diagnosis and treatment of SARS CoV infection. More specifically, the application discloses nucleic acids and peptides of the spike glycoprotein of SARS CoV that provide prognostic and therapeutic compositions in treatment of individuals contracting, or in danger of contracting SARS CoV. The peptides of the invention are also useful in producing antibodies against the SARS CoV glycoprotein.

摘要翻译： 本发明涉及免疫化学和药理学领域。 描述了SARS CoV感染的诊断和治疗方法和组成。 更具体地，该申请公开了SARS CoV的尖峰糖蛋白的核酸和肽，其提供治疗个体的预后和治疗组合物，这些个体承受或承受SARS CoV的危险。 本发明的肽也可用于产生针对SARS CoV糖蛋白的抗体。